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Clinical Trial
. 1988 Apr;27(4):313-7.
doi: 10.1016/0028-2243(88)90044-5.

Single-dose prophylaxis in gynaecological surgery: amoxycillin/clavulanic acid versus the combination of cefuroxim and metronidazole in a randomized prospective comparison

S Friese  1 , G J Pricker, F T Willems, S M Loriaux
Affiliations
Clinical Trial

Single-dose prophylaxis in gynaecological surgery: amoxycillin/clavulanic acid versus the combination of cefuroxim and metronidazole in a randomized prospective comparison

S Friese et al. Eur J Obstet Gynecol Reprod Biol. 1988 Apr.

Abstract

A prospective randomized study was conducted comparing a single 2.2 g preoperative dose amoxycillin/clavulanic acid with a regimen of 1.5 g cefuroxim combined with 0.5 g metronidazole. Two hundred and fifty-one women were evaluated in this comparative study. The febrile morbidity, the incidence of urinary tract infections and the hospital stay were similar in both regimens. A single preoperative dose of amoxycillin/clavulanic acid was as effective as a combined regimen of cefuroxim and metronidazole and less expensive.

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