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. 1988 Jan;2(1):96-8.
doi: 10.1016/0888-7543(88)90114-0.

The AKT1 proto-oncogene maps to human chromosome 14, band q32

S P Staal  1 , K Huebner, C M Croce, N Z Parsa, J R Testa
Affiliations

The AKT1 proto-oncogene maps to human chromosome 14, band q32

S P Staal et al. Genomics. 1988 Jan.

Abstract

The human AKT1 gene is the proto-oncogene of the viral oncogene v-akt. The AKT1 gene has been localized to human chromosome 14, band q32, proximal to the heavy-chain immunoglobulin locus (IGHM), by analysis of human-hamster somatic cell hybrids and by in situ hybridization. Chromosome rearrangements of this band which occur in T-lymphoid malignancies and Hodgkin's disease may affect the AKT1 gene.

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