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. 2021 Apr 13;143(15):1455-1457.
doi: 10.1161/CIRCULATIONAHA.120.052531. Epub 2021 Apr 12.

Unloading the Stenotic Path to Identifying Medical Therapy for Calcific Aortic Valve Disease: Barriers and Opportunities

Affiliations

Unloading the Stenotic Path to Identifying Medical Therapy for Calcific Aortic Valve Disease: Barriers and Opportunities

Brian R Lindman et al. Circulation. .
No abstract available

Keywords: aortic valve stenosis; clinical trial; diagnosis; heart valves; therapeutics.

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Figures

Figure
Figure
Unloading the Stenotic Path Toward Medical Therapy for Calcific Aortic Valve Disease (CAVD).

References

    1. Osnabrugge RL, Mylotte D, Head SJ, Van Mieghem NM, Nkomo VT, LeReun CM, Bogers AJ, Piazza N and Kappetein AP. Aortic stenosis in the elderly: disease prevalence and number of candidates for transcatheter aortic valve replacement: a meta-analysis and modeling study. J Am Coll Cardiol. 2013;62:1002–12. - PubMed
    1. Coffey S, Cox B and Williams MJ. The prevalence, incidence, progression, and risks of aortic valve sclerosis: a systematic review and meta-analysis. J Am Coll Cardiol. 2014;63:2852–61. - PubMed
    1. Hutcheson JD, Aikawa E and Merryman WD. Potential drug targets for calcific aortic valve disease. Nat Rev Cardiol. 2014;11:218–31. - PMC - PubMed
    1. Marquis-Gravel G, Redfors B, Leon MB and Genereux P. Medical Treatment of Aortic Stenosis. Circulation. 2016;134:1766–1784. - PubMed
    1. Boffa MB and Koschinsky ML. Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease. Nat Rev Cardiol. 2019;16:305–318. - PubMed

Publication types

Supplementary concepts