The potential of Apiaceae species as sources of singular phytochemicals and plant-based pesticides

Abstract

The Apiaceae Lindl. (=Umbelliferae Juss.), which includes several economical important vegetables, herbs, and spices, is one of the most numerous plant family. Umbelliferous crops (namely anise, fennel, carrot, coriander, parsley, etc.) are also valuable sources of botanical flavoring agents and fragrances. In addition, Apiaceae species yield a wide variety of distinctive specialized metabolites (i.e, volatile phenylpropanoids, furanocoumarins, sesquiterpene coumarins, polyacetylenes, and phthalides), some of them been described as uncommon natural phytochemicals exclusive of the family, which offers a great potential for bioprospection. Numerous studies have pointed out the outstanding biological activity of extracts and several classes of phytochemicals from Apiaceae species. Emphasis has been given to essential oils (EOs) and their constituents activities, most likely because this type of plant added value product benefits from a larger acceptance and application potential in integrated pest management (IPM) and integrated vector management (IVM) programs. Several species of the family offer a variety of unique compounds with great potential as biopesticidal and/or synergizing agents. Investigations covering their activity toward agricultural pests and phytopathogens have increased in the last years, nevertheless the interest remains strongly focus on arthropod species, predominantly those acting as vectors of human diseases. From our survey, it is patent the gap of knowledge concerning the potential molluscicidal properties of Apiaceae extracts/phytochemicals, as well as their herbicidal activities against invasive plant species. In this review, we propose to highlight the potential of Apiaceae species as suitable sources of bioactive phytochemicals with great relevance within the frame of plant-based pesticides R&D, and will discuss their applicability in real-world scenarios considering the recent developments regarding the design of stable formulations incorporating Apiaceae bioactive products. We expect that this review will encourage researchers to consider undervalued Apiaceae species as alternative sources of bioactive compounds and will give a contribute to the field by suggesting new research topics.

Keywords: Anti-arthropods; Antimicrobial; Furanocoumarins; Molluscicidal; Nematicidal; Phenylpropanoids; Phthalides; Phytotoxic; Plant-based pesticides; Terpenoids.