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. 2021 Apr 12;18(1):73.
doi: 10.1186/s12985-021-01546-8.

Heterogeneity of post-COVID impairment: interim analysis of a prospective study from Czechia

Mikulas Skala  1   2 , Michal Svoboda  3 , Michal Kopecky  1   2 , Eva Kocova  2   4 , Martin Hyrsl  4 , Michal Homolac  5 , Viktor Chrobok  2   5 , Pavel Bostik  2   6   7 , Miroslav Fajfr  6 , Petr Prasil  2   8 , Stanislav Plisek  2   8 , Radek Sleha  7 , Vladimir Koblizek  9   10
Affiliations

Heterogeneity of post-COVID impairment: interim analysis of a prospective study from Czechia

Mikulas Skala et al. Virol J. .

Abstract

We stratified post-COVID patients into four newly established clinical groups based on the presence or absence of at least one subjective respiratory symptom and at least one objective sign of pulmonary involvement. Nearly half of outpatients and one third of hospitalized post-COVID patients had objective signs of pulmonary involvement without accompanying subjective respiratory symptoms three months after diagnosis.

Keywords: 6-min Walk Test; Computer tomography; Lung function; Post-COVID; Symptom.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Left side: post-COVID stratification groups. (A) No respiratory symptoms, no objective signs of pulmonary involvement (PI), (B) respiratory symptoms without objective signs of PI, (C) no respiratory symptoms but objective signs of PI, (D) respiratory symptoms and objective signs of PI, (E) extra-pulmonary symptoms (additional mark to group A–D). Example of use—a patient with persistent cough and fatigue without objective signs of PI is classified as B/E. Right side: results of applied use of post-COVID stratification on our study patient cohort
See this image and copyright information in PMC

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