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. 2021 Apr 12;31(7):R337-R340.
doi: 10.1016/j.cub.2021.01.057.

Cancer biology: Messages in extracellular vesicles depend on centrosome number

Cayla E Jewett  1 , Chad G Pearson  2
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Cancer biology: Messages in extracellular vesicles depend on centrosome number

Cayla E Jewett et al. Curr Biol. .
Free article

Abstract

Extra centrosomes are linked to cancer-associated errors in cell division, metastasis and signaling. A new study reveals that centrosome amplification disrupts lysosome function, leading to the release of small extracellular vesicles and to invasive activity in pancreatic cells.

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