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. 2021 Apr 12;31(7):R347-R350.
doi: 10.1016/j.cub.2021.01.092.

Mechanobiology: Forging a strong matrix at tendons

Clara Sidor  1 , Frank Schnorrer  2
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Mechanobiology: Forging a strong matrix at tendons

Clara Sidor et al. Curr Biol. .
Free article

Abstract

Nature faces the challenge of stably attaching soft muscles to a stiff skeleton. A new study combines live imaging and fly genetics to reveal that mechanical tension and a putative intracellular chaperone assist in assembling the gigantic extracellular matrix protein Dumpy at fly tendon-skeleton interfaces.

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