doi: 10.1159/000231919.
Role of T and adherent cells in in vitro response of nude mouse spleen cells to bacterial lipopolysaccharide
- PMID: 338502
- DOI: 10.1159/000231919
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Role of T and adherent cells in in vitro response of nude mouse spleen cells to bacterial lipopolysaccharide
Int Arch Allergy Appl Immunol.
1977.
Abstract
Thy 1.2-positive cells and adherent cells were depleted from nude mouse spleen cell suspensions by treatment with anti-Thy 1.2 antisera plus complement and by passage through Sephadex G-10 column, respectively. The results of 3H-TdR uptake and appearance of IgM containing cells induced in vitro by lipopolysaccharide (LPS) were similar in both untreated and depleted spleen cells. Our findings confirm T and adherent cell independence of LPS response in nude mice.
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