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. 1977;55(1-6):131-4.
doi: 10.1159/000231919.

Role of T and adherent cells in in vitro response of nude mouse spleen cells to bacterial lipopolysaccharide

M Takigawa, M Hanaoka

Role of T and adherent cells in in vitro response of nude mouse spleen cells to bacterial lipopolysaccharide

M Takigawa et al. Int Arch Allergy Appl Immunol. 1977.

Abstract

Thy 1.2-positive cells and adherent cells were depleted from nude mouse spleen cell suspensions by treatment with anti-Thy 1.2 antisera plus complement and by passage through Sephadex G-10 column, respectively. The results of 3H-TdR uptake and appearance of IgM containing cells induced in vitro by lipopolysaccharide (LPS) were similar in both untreated and depleted spleen cells. Our findings confirm T and adherent cell independence of LPS response in nude mice.

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