Progress of Clinical Evaluation for Vascular Aging in Humans

doi:10.2478/jtim-2021-0002

Review

. 2021 Jan 5;9(1):17-23.

doi: 10.2478/jtim-2021-0002. eCollection 2021 Mar.

Progress of Clinical Evaluation for Vascular Aging in Humans

Yumin Qiu^{1

2

3}, Yuanya Liu^{1

2

3}, Jun Tao^{1

2

3}

Affiliations

¹ Department of Hypertension and Vascular Disease, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
² National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, Guangdong Province, China.
³ Key Laboratory on Assisted Circulation, Ministry of Health, Guangzhou, Guangdong Province, China.

PMID: 33850797
PMCID: PMC8016347
DOI: 10.2478/jtim-2021-0002

Review

Progress of Clinical Evaluation for Vascular Aging in Humans

Yumin Qiu et al. J Transl Int Med. 2021.

. 2021 Jan 5;9(1):17-23.

doi: 10.2478/jtim-2021-0002. eCollection 2021 Mar.

Authors

Yumin Qiu^{1

2

3}, Yuanya Liu^{1

2

3}, Jun Tao^{1

2

3}

Affiliations

¹ Department of Hypertension and Vascular Disease, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
² National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, Guangdong Province, China.
³ Key Laboratory on Assisted Circulation, Ministry of Health, Guangzhou, Guangdong Province, China.

PMID: 33850797
PMCID: PMC8016347
DOI: 10.2478/jtim-2021-0002

Abstract

Human society is experiencing a serious aging process. Age-related arteriosclerotic cardiovascular diseases (ASCVD) are the most common cause of deaths around the world and bring a huge burden on the whole society. Vascular aging-related pathological alterations of the vasculature play an important role in the pathogenesis of ASCVD and morbidity and mortality of older adults. In this review, we describe the progress of clinical evaluation of vascular aging in humans, including functional evaluation, structural assessment, and cellular molecular markers. The significance of detection for vascular aging is highlighted, and we call for close attention to the evaluation for a better quality of life in the elderly population.

Keywords: arteriosclerotic cardiovascular diseases; clinical evaluation; vascular aging.

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Conflict of interest statement

Conflict of Interest The authors declare no competing interests.

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References

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[1] Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a “set up” for vascular disease. Circulation. 2003;107:139–46. - PubMed

[2] Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a “set up” for vascular disease. Circulation. 2003;107:139–46. - PubMed

[3] Ungvari Z, Tarantini S, Donato AJ, Galvan V, Csiszar A. Mechanisms of Vascular Aging. Circ Res. 2018;123:849–67. - PMC - PubMed

[4] Ungvari Z, Tarantini S, Donato AJ, Galvan V, Csiszar A. Mechanisms of Vascular Aging. Circ Res. 2018;123:849–67. - PMC - PubMed

[5] Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y. et al. Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level: FMD-J Study (Flow-Mediated Dilation Japan) Hypertension. 2017;70:790–7. - PubMed

[6] Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y. et al. Endothelial Function Is Impaired in Patients Receiving Antihypertensive Drug Treatment Regardless of Blood Pressure Level: FMD-J Study (Flow-Mediated Dilation Japan) Hypertension. 2017;70:790–7. - PubMed

[7] Koivistoinen T, Lyytikainen LP, Aatola H, Luukkaala T, Juonala M, Viikari J. et al. Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults. Hypertension. 2018;71:451–6. - PubMed

[8] Koivistoinen T, Lyytikainen LP, Aatola H, Luukkaala T, Juonala M, Viikari J. et al. Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults. Hypertension. 2018;71:451–6. - PubMed

[9] Abboud H, Monteiro Tavares L, Labreuche J, Arauz A, Bryer A, Lavados PM. et al. Impact of Low Ankle-Brachial Index on the Risk of Recurrent Vascular Events. Stroke. 2019;50:853–8. - PubMed

[10] Abboud H, Monteiro Tavares L, Labreuche J, Arauz A, Bryer A, Lavados PM. et al. Impact of Low Ankle-Brachial Index on the Risk of Recurrent Vascular Events. Stroke. 2019;50:853–8. - PubMed

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Progress of Clinical Evaluation for Vascular Aging in Humans

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Progress of Clinical Evaluation for Vascular Aging in Humans

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