Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jul;64(1):E1-E2.
doi: 10.1002/mus.27251. Epub 2021 Apr 28.

Post COVID-19 vaccine small fiber neuropathy

Affiliations
Case Reports

Post COVID-19 vaccine small fiber neuropathy

Waqar Waheed et al. Muscle Nerve. 2021 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

None of the authors have any conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Three mm punch biopsies of skin undertaken confirmed multifocal small fiber neuropathy, suggested by loss of protein gene product 9.5 immunolabeled nerve fibers in the dorsum of left foot, over the extensor digitorum brevis muscle (2.1 fibers/mm of skin; normal >3.0) and left upper thigh at the level of ischial tuberosity (3.8 fibers/mm of skin; normal >6.0), and low normal intra‐epidermal nerve fiber density (IENFD) in the calf segment, 10 cm above the lateral malleolus (4.7 fibers/mm of skin; normal >4.3). Scale bar represents 20 μm. Interpretation of IENFD was done by Corinthian Reference Laboratory, Benbrook, TX [Color figure can be viewed at wileyonlinelibrary.com]

References

    1. Levine T. A proposed taxonomy of isolated small fiber neuropathy. RRNMF Neuromuscular J. 2020;1(4):18‐23. 10.17161/rrnmf.v1i4.13837. - DOI
    1. Kafaie J, Kim M, Krause E. Small fiber neuropathy following vaccination. J Clin Neuromuscul Dis. 2016;18:37‐40. - PubMed
    1. Salmon DA, Dudley MZ, Carleton BC. Guillain‐Barré syndrome following influenza vaccines affords opportunity to improve vaccine confidence. J Infect. 2021;223(3):355‐358. - PMC - PubMed
    1. Keddie S, Pakpoor J, Mousele C, et al. Epidemiological and cohort study finds no association between COVID‐19 and Guillain‐Barré syndrome. Brain. 2020;144(2):682‐693. - PMC - PubMed
    1. Shimabukuro T. COVID‐19 vaccine safety update. Advisory Committee on Immunization Practices (ACIP) meeting, January 27, 2021. https://www‐cdc‐gov.ezproxy.uvm.edu/vaccines/acip/meetings/downloads/sli.... Accessed January 28, 2021

MeSH terms

Substances