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Comment
. 2021 Jun;46(6):431-432.
doi: 10.1016/j.tibs.2021.03.004. Epub 2021 Apr 12.

More Than Just Letters and Chemistry: Genomics Goes Mechanics

Sebastian Deindl  1 , Johan Elf  2
Affiliations
Comment

More Than Just Letters and Chemistry: Genomics Goes Mechanics

Sebastian Deindl et al. Trends Biochem Sci. 2021 Jun.

Abstract

Although ubiquitously thought of as a simple string of letters, DNA exhibits complex physicochemical properties. As a result, DNA can store information beyond the extensively studied explicit genetic message. The mechanical code of DNA has not been studied systematically in a genome-wide context until recent groundbreaking work by Basu et al.

Keywords: DNA mechanics.

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Conflict of interest statement

Declaration of Interests No interests are declared.

Comment on

  • Measuring DNA mechanics on the genome scale.
    Basu A, Bobrovnikov DG, Qureshi Z, Kayikcioglu T, Ngo TTM, Ranjan A, Eustermann S, Cieza B, Morgan MT, Hejna M, Rube HT, Hopfner KP, Wolberger C, Song JS, Ha T. Basu A, et al. Nature. 2021 Jan;589(7842):462-467. doi: 10.1038/s41586-020-03052-3. Epub 2020 Dec 16. Nature. 2021. PMID: 33328628 Free PMC article.

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