Essential updates 2019/2020: Surgical treatment of gallbladder cancer
- PMID: 33860135
- PMCID: PMC8034687
- DOI: 10.1002/ags3.12434
Essential updates 2019/2020: Surgical treatment of gallbladder cancer
Abstract
Gallbladder cancer is a biliary tract cancer that originates in the gallbladder and cystic ducts and is recognized worldwide as a refractory cancer with early involvement of the surrounding area because of its anatomical characteristics. Although the number of cases is increasing steadily worldwide, the frequency of this disease remains low, making it difficult to plan large-scale clinical studies, and there is still much discussion about the indications for surgical resection and the introduction of multidisciplinary treatment. Articles published between 2019 and 2020 were reviewed, focusing mainly on the indications for surgical resection for each tumor stage, the treatment of incidental gallbladder cancer, and current trends in minimally invasive surgery for gallbladder cancer.
Keywords: IGBC; gallbladder cancer; minimally invasive surgery; neoadjuvant chemotherapy; surgical strategy.
© 2021 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterology.
Conflict of interest statement
Conflict of Interest: The authors declare no conflicts of interest for this article. Author Contribution: Itaru Endo devised this project, the main conceptual ideas, and the proof outline. Ryusei Matsuyama selected and reviewed references and wrote the initial draft of the manuscript. Yasuhiro Yabushita, Yuki Homma, and Takafumi Kumamoto contributed to review of the references and assisted in the presentation of the manuscript. All authors critically reviewed the manuscript.
Similar articles
-
Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC) - a phase III study of the German registry of incidental gallbladder carcinoma platform (GR)- the AIO/ CALGP/ ACO- GAIN-trial.BMC Cancer. 2020 Feb 14;20(1):122. doi: 10.1186/s12885-020-6610-4. BMC Cancer. 2020. PMID: 32059704 Free PMC article. Clinical Trial.
-
Incidental gallbladder cancer diagnosis confers survival advantage irrespective of tumour stage and characteristics.World J Gastroenterol. 2022 May 14;28(18):1996-2007. doi: 10.3748/wjg.v28.i18.1996. World J Gastroenterol. 2022. PMID: 35664962 Free PMC article.
-
Predictive factors for incidental gallbladder cancer (IGBC) in patients undergoing cholecystectomy for presumed benign disease. A single-center experience.Ann Ital Chir. 2018;89:118-127. Ann Ital Chir. 2018. PMID: 29848815
-
Selecting treatment sequence for patients with incidental gallbladder cancer: a neoadjuvant approach versus upfront surgery.Updates Surg. 2019 Jun;71(2):217-225. doi: 10.1007/s13304-019-00670-z. Epub 2019 Jun 28. Updates Surg. 2019. PMID: 31254234 Review.
-
Minimally Invasive Surgery for Gallbladder Cancer.Surg Oncol Clin N Am. 2019 Apr;28(2):243-253. doi: 10.1016/j.soc.2018.11.001. Epub 2019 Feb 2. Surg Oncol Clin N Am. 2019. PMID: 30851826 Review.
Cited by
-
Neoadjuvant treatment for incidental gallbladder cancer: A systematic review.Ann Hepatobiliary Pancreat Surg. 2025 May 31;29(2):113-120. doi: 10.14701/ahbps.24-223. Epub 2025 Mar 11. Ann Hepatobiliary Pancreat Surg. 2025. PMID: 40064481 Free PMC article. Review.
-
A prospective observational study of laparoscopic approaches for suspected gallbladder cancer in Yamaguchi (YPB-002 LAGBY).Updates Surg. 2025 Apr;77(2):435-445. doi: 10.1007/s13304-025-02119-y. Epub 2025 Feb 24. Updates Surg. 2025. PMID: 39992576
-
Differential diagnoses of gallbladder tumors using CT-based deep learning.Ann Gastroenterol Surg. 2022 Jun 11;6(6):823-832. doi: 10.1002/ags3.12589. eCollection 2022 Nov. Ann Gastroenterol Surg. 2022. PMID: 36338581 Free PMC article.
-
Disease burden of biliary tract cancer in 204 countries and territories, 1990-2021: A comprehensive demographic analysis of the Global Burden of Disease Study 2021.Chin Med J (Engl). 2024 Dec 20;137(24):3117-3125. doi: 10.1097/CM9.0000000000003395. Epub 2024 Dec 17. Chin Med J (Engl). 2024. PMID: 39682017 Free PMC article.
-
A case of successful conversion surgery for unresectable gallbladder cancer treated with durvalumab in combination with gemcitabine plus cisplatin.Clin J Gastroenterol. 2025 Feb;18(1):161-168. doi: 10.1007/s12328-024-02053-3. Epub 2024 Oct 22. Clin J Gastroenterol. 2025. PMID: 39436624
References
-
- Parkin DM, Muir CS, Whelan SL, Gao YT, Ferlay J, Powell J, et al. Cancer incidence in five continents, Vol. Ⅵ. IARC , editor. Lyon: IARC Scientific Publications, No 120; 1992.
-
- Vo E, Curley SA, Chai CY, Massarweh NN, Tran Cao HS. National failure of surgical staging for T1b gallbladder cancer. Ann Surg Oncol. 2019;26(2):604–10. - PubMed
-
- Xu L, Tan H, Liu X, Huang J, Liu L, Si S, et al. Survival benefits of simple versus extended cholecystectomy and lymphadenectomy for patients with T1b gallbladder cancer: An analysis of the surveillance, epidemiology, and end results database (2004 to 2013). Cancer Med. 2020;9(11):3668–79. - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources