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Review
. 2021 Jan 29;5(2):152-161.
doi: 10.1002/ags3.12434. eCollection 2021 Mar.

Essential updates 2019/2020: Surgical treatment of gallbladder cancer

Affiliations
Review

Essential updates 2019/2020: Surgical treatment of gallbladder cancer

Ryusei Matsuyama et al. Ann Gastroenterol Surg. .

Abstract

Gallbladder cancer is a biliary tract cancer that originates in the gallbladder and cystic ducts and is recognized worldwide as a refractory cancer with early involvement of the surrounding area because of its anatomical characteristics. Although the number of cases is increasing steadily worldwide, the frequency of this disease remains low, making it difficult to plan large-scale clinical studies, and there is still much discussion about the indications for surgical resection and the introduction of multidisciplinary treatment. Articles published between 2019 and 2020 were reviewed, focusing mainly on the indications for surgical resection for each tumor stage, the treatment of incidental gallbladder cancer, and current trends in minimally invasive surgery for gallbladder cancer.

Keywords: IGBC; gallbladder cancer; minimally invasive surgery; neoadjuvant chemotherapy; surgical strategy.

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Conflict of interest statement

Conflict of Interest: The authors declare no conflicts of interest for this article. Author Contribution: Itaru Endo devised this project, the main conceptual ideas, and the proof outline. Ryusei Matsuyama selected and reviewed references and wrote the initial draft of the manuscript. Yasuhiro Yabushita, Yuki Homma, and Takafumi Kumamoto contributed to review of the references and assisted in the presentation of the manuscript. All authors critically reviewed the manuscript.

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References

    1. Parkin DM, Muir CS, Whelan SL, Gao YT, Ferlay J, Powell J, et al. Cancer incidence in five continents, Vol. Ⅵ. IARC , editor. Lyon: IARC Scientific Publications, No 120; 1992.
    1. Benson AB 3rd, Abrams TA, Ben‐Josef E, Bloomston PM, Botha JF, Clary BM, et al. NCCN clinical practice guidelines in oncology: hepatobiliary cancers. J Natl Compr Cancer Network. 2009;7(4):350–91. - PMC - PubMed
    1. Vo E, Curley SA, Chai CY, Massarweh NN, Tran Cao HS. National failure of surgical staging for T1b gallbladder cancer. Ann Surg Oncol. 2019;26(2):604–10. - PubMed
    1. Xu L, Tan H, Liu X, Huang J, Liu L, Si S, et al. Survival benefits of simple versus extended cholecystectomy and lymphadenectomy for patients with T1b gallbladder cancer: An analysis of the surveillance, epidemiology, and end results database (2004 to 2013). Cancer Med. 2020;9(11):3668–79. - PMC - PubMed
    1. Yuza K, Sakata J, Prasoon P, Hirose Y, Ohashi T, Toge K, et al. Long‐term outcomes of surgical resection for T1b gallbladder cancer: an institutional evaluation. BMC Cancer. 2020;20(1):20. - PMC - PubMed

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