Constructing the rodent stereotaxic brain atlas: a survey

Zhao Feng^{1

2}, Anan Li^{1

2}, Hui Gong^{3

4}, Qingming Luo^{5

6

7}

Affiliations

¹ Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MOE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, 430074, China.
² HUST-Suzhou Institute for Brainsmatics, Suzhou, 215123, China.
³ Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MOE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, 430074, China. huigong@mail.hust.edu.cn.
⁴ HUST-Suzhou Institute for Brainsmatics, Suzhou, 215123, China. huigong@mail.hust.edu.cn.
⁵ Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MOE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, 430074, China. qluo@hainanu.edu.cn.
⁶ HUST-Suzhou Institute for Brainsmatics, Suzhou, 215123, China. qluo@hainanu.edu.cn.
⁷ School of Biomedical Engineering, Hainan University, Haikou, 570228, China. qluo@hainanu.edu.cn.

PMID: 33860452
DOI: 10.1007/s11427-020-1911-9

Review

Constructing the rodent stereotaxic brain atlas: a survey

Zhao Feng et al. Sci China Life Sci. 2022 Jan.

. 2022 Jan;65(1):93-106.

doi: 10.1007/s11427-020-1911-9. Epub 2021 Apr 13.

Authors

Zhao Feng^{1

2}, Anan Li^{1

2}, Hui Gong^{3

4}, Qingming Luo^{5

6

7}

Affiliations

¹ Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MOE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, 430074, China.
² HUST-Suzhou Institute for Brainsmatics, Suzhou, 215123, China.
³ Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MOE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, 430074, China. huigong@mail.hust.edu.cn.
⁴ HUST-Suzhou Institute for Brainsmatics, Suzhou, 215123, China. huigong@mail.hust.edu.cn.
⁵ Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MOE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, 430074, China. qluo@hainanu.edu.cn.
⁶ HUST-Suzhou Institute for Brainsmatics, Suzhou, 215123, China. qluo@hainanu.edu.cn.
⁷ School of Biomedical Engineering, Hainan University, Haikou, 570228, China. qluo@hainanu.edu.cn.

PMID: 33860452
DOI: 10.1007/s11427-020-1911-9

Abstract

The stereotaxic brain atlas is a fundamental reference tool commonly used in the field of neuroscience. Here we provide a brief history of brain atlas development and clarify three key conceptual elements of stereotaxic brain atlasing: brain image, atlas, and stereotaxis. We also refine four technical indices for evaluating the construction of atlases: the quality of staining and labeling, the granularity of delineation, spatial resolution, and the precision of spatial location and orientation. Additionally, we discuss state-of-the-art technologies and their trends in the fields of image acquisition, stereotaxic coordinate construction, image processing, anatomical structure recognition, and publishing: the procedures of brain atlas illustration. We believe that the use of single-cell resolution and micron-level location precision will become a future trend in the study of the stereotaxic brain atlas, which will greatly benefit the development of neuroscience.

Keywords: brain atlas; brainsmatics; cytoarchitecture; stereotaxic.

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Constructing the rodent stereotaxic brain atlas: a survey

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Constructing the rodent stereotaxic brain atlas: a survey

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