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. 2021 Aug;17(8):1307-1316.
doi: 10.1002/alz.12297. Epub 2021 Apr 15.

Identification of undiagnosed dementia cases using a web-based pre-screening tool: The MOPEAD project

Adrián Rodrigo  1 , Paloma Trigueros  1 , Laura Jamilis  1 , Montserrat Alegret  2   3 , Octavio Rodríguez  2 , Lluís Tárraga  2   3 , Antonio González-Pérez  2 , Milica Kramberger  4 , Bengt Winblad  5   6 , Pieter Jelle Visser  7   8 , Frank Jessen  9 , Laura Campo  10 , Mercè Boada  2   3 ; MOPEAD consortium
Affiliations

Identification of undiagnosed dementia cases using a web-based pre-screening tool: The MOPEAD project

Adrián Rodrigo et al. Alzheimers Dement. 2021 Aug.

Abstract

Introduction: Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are "hidden" in their communities and not normally found in a memory clinic setting.

Methods: A marketing campaign and a web-based pre-screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project.

Results: A total of 1487 individuals completed the pre-screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre-screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease.

Conclusion: This novel web-based pre-screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.

Keywords: Alzheimer's disease; diagnostic gap; early diagnosis; patient engagement; population-based screening.

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Conflict of interest statement

Laura Campo is a full‐time employee of Eli Lilly Italia S.p.A. and shareholder of Eli Lilly.

Figures

FIGURE 1
FIGURE 1
Funnel plot from visits to Alzheimer's disease/mild cognitive impairment (MCI) cases
See this image and copyright information in PMC

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