Challenges in CNS drug development and the role of imaging

Oliver D Howes^{1

2

3}, Mitul A Mehta⁴

Affiliations

¹ Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. oliver.howes@kcl.ac.uk.
² MRC London Institute for Medical Sciences, Hammersmith Hospital, London, UK. oliver.howes@kcl.ac.uk.
³ Translational Neuropsychiatry, H Lundbeck A/S, Valby, Denmark. oliver.howes@kcl.ac.uk.
⁴ Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Editorial

Oliver D Howes et al. Psychopharmacology (Berl). 2021 May.

. 2021 May;238(5):1229-1230.

doi: 10.1007/s00213-021-05838-3.

Oliver D Howes^{1

2

3}, Mitul A Mehta⁴

¹ Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. oliver.howes@kcl.ac.uk.
² MRC London Institute for Medical Sciences, Hammersmith Hospital, London, UK. oliver.howes@kcl.ac.uk.
³ Translational Neuropsychiatry, H Lundbeck A/S, Valby, Denmark. oliver.howes@kcl.ac.uk.
⁴ Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

No abstract available

Comment on

Time to re-engage psychiatric drug discovery by strengthening confidence in preclinical psychopharmacology.
Tricklebank MD, Robbins TW, Simmons C, Wong EHF. Tricklebank MD, et al. Psychopharmacology (Berl). 2021 Jun;238(6):1417-1436. doi: 10.1007/s00213-021-05787-x. Epub 2021 Mar 10. Psychopharmacology (Berl). 2021. PMID: 33694032 Free PMC article. Review.

1. Blest-Hopley G, O’Neill A, Wilson R, Giampietro V, Bhattacharyya S (2021) https://doi.org/10.1007/s00213-019-05407-9
1. Egerton A (2021) https://doi.org/10.1007/s00213-019-05344-7
1. Gilleen J, Farah Y, Davison C, Kerins S, Valdearenas L, Uz T, Lahu G, Tsai M, Ogrinc F, Reichenberg A, Williams SC, Mehta MA, Shergill SS (2021) https://doi.org/10.1007/s00213-018-5134-y
1. Godlewska BR, Harmer CJ (2021) https://doi.org/10.1007/s00213-019-05448-0
1. Grimm O, Nägele M, Küpper-Tetzel L, de Greck M, Plichta M, Reif A (2021) https://doi.org/10.1007/s00213-020-05693-8