Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul 1;137(26):3674-3676.
doi: 10.1182/blood.2021011904.

Low neutralizing antibody responses against SARS-CoV-2 in older patients with myeloma after the first BNT162b2 vaccine dose

Affiliations

Low neutralizing antibody responses against SARS-CoV-2 in older patients with myeloma after the first BNT162b2 vaccine dose

Evangelos Terpos et al. Blood. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Kinetics of NAbs in elderly patients with myeloma and age-matched controls after vaccination with the first dose of the BNT162b2 mRNA vaccine. On D22, patients with myeloma had lower production of NAb inhibition titers compared with controls of similar age and sex. Only 4 patients with myeloma had NAb titers ≥50%. POS, positivity threshold.

References

    1. Dumontet C, Hulin C, Dimopoulos MA, et al. . A predictive model for risk of early grade ≥ 3 infection in patients with multiple myeloma not eligible for transplant: analysis of the FIRST trial. Leukemia. 2018;32(6):1404-1413. - PMC - PubMed
    1. Martínez-López J, Mateos MV, Encinas C, et al. . Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality. Blood Cancer J. 2020;10(10):103. - PMC - PubMed
    1. Engelhardt M, Shoumariyeh K, Rösner A, et al. . Clinical characteristics and outcome of multiple myeloma patients with concomitant COVID-19 at Comprehensive Cancer Centers in Germany. Haematologica. 2020;105(12):2872-2878. - PMC - PubMed
    1. Chari A, Samur MK, Martinez-Lopez J, et al. . Clinical features associated with COVID-19 outcome in multiple myeloma: first results from the International Myeloma Society data set. Blood. 2020;136(26):3033-3040. - PMC - PubMed
    1. Gavriatopoulou M, Ntanasis-Stathopoulos I, Korompoki E, et al. . Emerging treatment strategies for COVID-19 infection. Clin Exp Med. 2021;21(2):167-179. - PMC - PubMed

MeSH terms