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. 2021 Apr 15;184(8):1965-1967.
doi: 10.1016/j.cell.2021.03.045.

Founder cells shape brain evolution

Jing Liu  1 , Debra L Silver  2
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Founder cells shape brain evolution

Jing Liu et al. Cell. .
Free article

Abstract

Humans have an extraordinarily expanded and complex cerebral cortex, relative to non-human primates. Yet the mechanisms underlying cortical differences across evolution are unclear. A new study by Benito-Kwiecinski et al. employs cerebral organoids derived across great apes to implicate neuroepithelial progenitor shape transitions in human cortical expansion.

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