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Case Reports
. 2021 Jul;75(1):222-224.
doi: 10.1016/j.jhep.2021.04.003. Epub 2021 Apr 20.

Autoimmune hepatitis developing after coronavirus disease 2019 (COVID-19) vaccine: Causality or casualty?

Fernando Bril  1 , Sameer Al Diffalha  2 , Mark Dean  3 , David M Fettig  4
Affiliations
Case Reports

Autoimmune hepatitis developing after coronavirus disease 2019 (COVID-19) vaccine: Causality or casualty?

Fernando Bril et al. J Hepatol. 2021 Jul.
No abstract available

Keywords: SARS-CoV-2; coronavirus; liver injury; mRNA vaccines.

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Conflict of interest statement

Conflict of interests The authors declare no conflicts of interest that pertain to this work. Please refer to the accompanying ICMJE disclosure forms for further details.

Figures

Fig. 1
Fig. 1
Histological (H&E stain) and biochemical findings. (A) Low-magnification (40x) shows pan-lobular hepatitis (black arrows: portal inflammation and yellow arrows: lobular inflammation). (B) Medium-magnification images (200x) show a portal tract with an intense lymphoplasmacytic infiltrate effacing the interface with rosette formation and (C) lobular activity with scattered hepatocyte necrosis (Black circle: acidophilic bodies). (D) At high magnification (600x), the inflammation consists primarily of lymphocytes with plasma cells (black arrowheads) and eosinophils (yellow arrowheads). (E) Trends of plasma ALT, AST and total bilirubin over time.
See this image and copyright information in PMC

Comment in

References

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