Infections in Older Adults
- PMID: 33863466
- DOI: 10.1016/j.emc.2021.01.004
Infections in Older Adults
Abstract
Infections in elderly patients can prove diagnostically challenging. Age-related factors affecting the immune system in older individuals contribute to nonspecific presentations. Other age-related factors and chronic conditions have symptoms that may or may not point to an infectious diagnosis. Delay in administration of antimicrobials can lead to poor outcomes; however, unnecessary administration of antimicrobials can lead to increased morbidity and contribute to the emergence of multidrug-resistant organisms. Careful clinical assessment and consideration of patient history and risk factors is crucial. When necessary, antimicrobials should be chosen that are appropriate for the diagnosis and deescalated as soon as possible.
Keywords: Antimicrobial stewardship; Elderly; Emergency department; Gastrointestinal infections; Infections; Pneumonia; Skin and soft tissue infections; Urinary tract infection.
Copyright © 2021 Elsevier Inc. All rights reserved.
Conflict of interest statement
Disclosure MMS and SYL have no conflicts of interest to disclose. SYL received support through the Foundation for Barnes-Jewish Hospital and the Washington University Institute of Clinical and Translational Sciences which is, in part, supported by the NIH/National Center for Advancing Translational Sciences (NCATS), Clinical and Translational Science Award (CTSA) program (UL1TR002345).
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