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Review
. 2021 May;41(2):165-175.
doi: 10.1016/j.iac.2021.01.001. Epub 2021 Mar 26.

The Phenotype of the Food-Allergic Patient

Amy A Eapen  1 , Haejin Kim  2
Affiliations
Review

The Phenotype of the Food-Allergic Patient

Amy A Eapen et al. Immunol Allergy Clin North Am. 2021 May.

Abstract

Food allergy's increasing prevalence across the globe has initiated research into risk factors associated with the disease and coexistence with other allergic diseases. Longitudinal birth cohorts have identified food allergy phenotypes of patients based on genetic background, racial diversity, and environmental factors. Identifying food sensitization patterns and coexistence of other allergic diseases allows physicians to provide appropriate care for food allergy and personalized anticipatory guidance for the appearance of other allergic diseases. The authors seek to detail key findings of 4 longitudinal allergy birth cohorts that investigate food allergy and other allergic diseases to further characterize food allergy phenotypes.

Keywords: Atopic march; Birth cohorts; Food allergy; Food sensitization.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

Figures

Figure 1.
Figure 1.
Food allergy phenotypes/determinants. Figure details phenotypes detailed by allergy birth cohort data from 4 cohorts: WEHALS, CCAPS, HEALTHNUTS, and PASTURE.
See this image and copyright information in PMC

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References

    1. Sicherer SH, Sampson HA. Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. J Allergy Clin Immunol. 2018;141(1):41–58. - PubMed
    1. McGowan EC, Keet CA. Prevalence of self-reported food allergy in the National Health and Nutrition Examination Survey (NHANES) 2007–2010. J Allergy Clin Immunol. 2013;132(5):1216–1219 e1215. - PMC - PubMed
    1. Savage J, Johns CB. Food allergy: epidemiology and natural history. Immunol Allergy Clin North Am. 2015;35(1):45–59. - PMC - PubMed
    1. Liu X, Hong X, Tsai HJ, et al. Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Medicine (Baltimore). 2018;97(9):e0043. - PMC - PubMed
    1. Tsai HJ, Kumar R, Pongracic J, et al. Familial aggregation of food allergy and sensitization to food allergens: a family-based study. Clin Exp Allergy. 2009;39(1):101–109. - PMC - PubMed

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