[Determination of effective renal plasma flow based on data from dynamic renoscintigraphy with 131I-hippuran]

Abstract

The paper is concerned with a comparative study of 2 methods of calculation of the separate effective renal plasma flow (ERPF)--by hippuran clearance and hippuran absorption by the kidneys on the 2nd minute of renoscintigraphic investigation. The latter one was characterized by some advantages: the use of routine scintigraphy, the absence of blood and urine tests, rapid performance, the accuracy of the results obtained was no inferior to that of ERPF calculation by clearance. The method was included in an application package for scintigraphy data processing. A study of the ERPF was conducted in 140 patients with nephroureterolithiasis in the time course of surgical treatment. The results have shown that the ERPF can be used not only for the control of therapeutic efficacy but also for the prognosis of postoperative restoration of affected kidney function. The determination of the total ERPF and a degree of asymmetry of its distribution is of great prognostic importance.