. 2021 Aug;21(8):2913-2915.

doi: 10.1111/ajt.16607. Epub 2021 May 7.

Immunogenicity of SARS-CoV-2 BNT162b2 vaccine in solid organ transplant recipients

Smaragdi Marinaki¹, Stamatis Adamopoulos², Dimitrios Degiannis³, Sotirios Roussos⁴, Ioanna D Pavlopoulou⁵, Angelos Hatzakis⁶, Ioannis N Boletis¹

Affiliations

¹ Clinic of Nephrology and Renal Transplantation NKUA, Medical School, Laiko General Hospital, Athens, Greece.
² Heart Failure and Transplant Units, Onassis Cardiac Surgery Center, Athens, Greece.
³ Molecular Immunopathology and Histocompatibility Unit, Onassis Cardiac Surgery Center, Athens, Greece.
⁴ Department of Hygiene, Epidemiology and Medical Statistics NKUA, Medical School, Athens, Greece.
⁵ Pediatric Research Laboratory, Faculty of Nursing, NKUA, School of Health Sciences, Athens, Greece.
⁶ Hellenic Scientific Society for the Study of AIDS, Sexually Transmitted and Emerging Diseases, Athens, Greece.

PMID: 33864722
PMCID: PMC8250574
DOI: 10.1111/ajt.16607

Immunogenicity of SARS-CoV-2 BNT162b2 vaccine in solid organ transplant recipients

Smaragdi Marinaki et al. Am J Transplant. 2021 Aug.

. 2021 Aug;21(8):2913-2915.

doi: 10.1111/ajt.16607. Epub 2021 May 7.

Authors

Smaragdi Marinaki¹, Stamatis Adamopoulos², Dimitrios Degiannis³, Sotirios Roussos⁴, Ioanna D Pavlopoulou⁵, Angelos Hatzakis⁶, Ioannis N Boletis¹

Affiliations

¹ Clinic of Nephrology and Renal Transplantation NKUA, Medical School, Laiko General Hospital, Athens, Greece.
² Heart Failure and Transplant Units, Onassis Cardiac Surgery Center, Athens, Greece.
³ Molecular Immunopathology and Histocompatibility Unit, Onassis Cardiac Surgery Center, Athens, Greece.
⁴ Department of Hygiene, Epidemiology and Medical Statistics NKUA, Medical School, Athens, Greece.
⁵ Pediatric Research Laboratory, Faculty of Nursing, NKUA, School of Health Sciences, Athens, Greece.
⁶ Hellenic Scientific Society for the Study of AIDS, Sexually Transmitted and Emerging Diseases, Athens, Greece.

PMID: 33864722
PMCID: PMC8250574
DOI: 10.1111/ajt.16607

No abstract available

Keywords: clinical research/practice; heart transplantation/cardiology; infection and infectious agents - viral; infectious disease; kidney transplantation/nephrology; vaccine.

PubMed Disclaimer

Figures

**FIGURE 1**
Anti-SARS-CoV-2 RBD IgG concentration (AU/ml) in organ transplant recipients (OTR) in comparison with health-care workers (HCW). Diamonds and endpoints of the rectangles represent median concentration and 25th–75th percentile, respectively. Dashed horizontal line indicates the assay limit of detection (LOD) 50 AU/ml [Color figure can be viewed at wileyonlinelibrary.com]

See this image and copyright information in PMC

Cited by

Humoral and cellular immune response to SARS-CoV-2 mRNA BNT162b2 vaccine in pediatric kidney transplant recipients compared with dialysis patients and healthy children.
Gulmez R, Ozbey D, Agbas A, Aksu B, Yildiz N, Uckardes D, Saygili S, Yilmaz EK, Yildirim ZY, Tasdemir M, Kiykim A, Cokugras H, Canpolat N, Nayir A, Kocazeybek B, Caliskan S. Gulmez R, et al. Pediatr Nephrol. 2023 Jul;38(7):2199-2208. doi: 10.1007/s00467-022-05813-w. Epub 2022 Dec 2. Pediatr Nephrol. 2023. PMID: 36459243 Free PMC article.
Humoral immunity against SARS-CoV-2 variants including omicron in solid organ transplant recipients after three doses of a COVID-19 mRNA vaccine.
Saharia KK, Husson JS, Niederhaus SV, Iraguha T, Avila SV, Yoo YJ, Hardy NM, Fan X, Omili D, Crane A, Carrier A, Xie WY, Vander Mause E, Hankey K, Bauman S, Lesho P, Mannuel HD, Ahuja A, Mathew M, Avruch J, Baddley J, Goloubeva O, Shetty K, Dahiya S, Rapoport AP, Luetkens T, Atanackovic D. Saharia KK, et al. Clin Transl Immunology. 2022 Apr 29;11(5):e1391. doi: 10.1002/cti2.1391. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35505864 Free PMC article.
Covid-19 vaccine immunogenicity in people living with HIV-1.
Nault L, Marchitto L, Goyette G, Tremblay-Sher D, Fortin C, Martel-Laferrière V, Trottier B, Richard J, Durand M, Kaufmann D, Finzi A, Tremblay C. Nault L, et al. Vaccine. 2022 Jun 9;40(26):3633-3637. doi: 10.1016/j.vaccine.2022.04.090. Epub 2022 May 5. Vaccine. 2022. PMID: 35568588 Free PMC article.
Outcome of SARS-CoV-2 variant breakthrough infection in fully immunized solid organ transplant recipients.
Almaghrabi RS, Alhamlan FS, Dada A, Al-Tawfiq JA, Al Hroub MK, Saeedi MF, Alamri M, Alhothaly B, Alqasabi A, Al-Qahtani AA, Al-Omari A, Alshukairi AN. Almaghrabi RS, et al. J Infect Public Health. 2022 Jan;15(1):51-55. doi: 10.1016/j.jiph.2021.11.021. Epub 2021 Dec 4. J Infect Public Health. 2022. PMID: 34906898 Free PMC article.
Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine.
Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE Jr, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Kramer KJ, et al. Nat Commun. 2022 Jun 16;13(1):3466. doi: 10.1038/s41467-022-31142-5. Nat Commun. 2022. PMID: 35710908 Free PMC article.

See all "Cited by" articles

References

1. Williamson EJ, Walker AJ, Bhaskaran K, et al. Factors associated with COVID-19-related death using Open SAFELY. Nature. 2020;584:430–436. - PMC - PubMed
1. Kumar D, Blumberg EA, Danziger-Isakov L, et al. Influenza vaccination in the organ transplant recipient: review and summary recommendations. Am J Transplant. 2011;11:2020–2030. - PubMed
1. Perkmann T, Nagele-Perkmen W, Koller T,. et al. Anti-Spike protein assays to determine post vaccination antibody levels: a head to head comparison of five quantitative assays. MedRxiv. 2021. 10.1101/2021.03.05.21252977. - DOI - PMC - PubMed
1. Boyarsky BJ, Werbel WA, Avery RK, et al. Immunogenicity of a single dose of SARS-CoV-2 messenger RNA vaccine in solid organ transplant recipients. JAMA. Published online March 15, 2021. 2021. 2021. 10.1001/jama.2021.4385. - DOI - PMC - PubMed
1. Walsh EE, Frenck RW, Falsey AR, et al. Safety and immunogenicity of two RNA-based Covid-19 vaccine candidates. N Engl J Med. 2020;383(25):2439–2450. - PMC - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

Grants and funding

704/13.01.2021/Onassis Cardiac Surgery Center

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations
Medical
- MedlinePlus Health Information
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Immunogenicity of SARS-CoV-2 BNT162b2 vaccine in solid organ transplant recipients

Affiliations

Immunogenicity of SARS-CoV-2 BNT162b2 vaccine in solid organ transplant recipients

Authors

Affiliations

Figures

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Miscellaneous