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. 2021 Mar-Apr;73(2):143-148.
doi: 10.1016/j.ihj.2020.11.147. Epub 2020 Nov 23.

Prognostic implications of thyroid hormone alterations in acute coronary syndrome-A systematic review

Priyadarshini Arambam  1 , Upendra Kaul  2 , Priya Ranjan  3 , Rajiv Janardhanan  4
Affiliations

Prognostic implications of thyroid hormone alterations in acute coronary syndrome-A systematic review

Priyadarshini Arambam et al. Indian Heart J. 2021 Mar-Apr.

Abstract

There is considerable association of thyroid function and the cardiovascular system during various acute systemic illnesses. It is well established that the normal thyroid homeostasis is known to alter in disease states including the acute coronary syndromes (ACS). Abnormal thyroid hormonal status has been shown to be related to worse outcomes and prognosis. This review focuses on the relationship of alterations in thyroid function and its influence on the pathophysiological mechanisms and cardiovascular hemodynamics in ACS and based upon the literature, summarises all the existing evidence to this date on this subject. The data largely points out that low levels of triiodothyronine (T3) levels seen in ACS might be useful in prognosticating the outcomes of ACS.

Keywords: Cardiovascular; Hypothyroidism; NSTEMI; STEMI; Thyroid hormone.

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Conflict of interest statement

Conflict of interest Miss Priyadarshini Arambam declares that she has no conflict of interest with any authors listed in the paper, Dr. Upendra Kaul declares that he has no conflict of interest with any authors listed in the paper, Dr. Priya Ranjan declares that he has no conflict of interest with any authors listed in the paper and Dr. Rajiv Janardhanan declares that he has no conflict of interest with any authors listed in the paper.

References

    1. Khalil O., Abdelaziz A., Ghoniem Md. Thyroid dysfunction in acute coronary syndrome and its relation to morbidity and mortality. Int J Sci Res. 2015;4:2319–7064.
    1. Farwell A.P. Nonthyroidal illness syndrome. Curr Opin Endocrinol Diabetes Obes. 2013;20:478–484. - PubMed
    1. Alevizaki M., Synetou M., Xynos K. Low triiodothyronine: a strong predictor of outcome in acute stroke patients. Eur J Clin Invest. 2007;37:6510–6657. - PubMed
    1. Pimentel R.C., Cardoso G.P., Escosteguy C.C. Thyroid hormone profile in acute coronary syndromes. Arq Bras Cardiol. 2006;87:688–694. - PubMed
    1. Friberg L., Werner S., Eggertsen G. Rapid down-regulation of thyroid hormones in acute myocardial infarction: is it cardioprotective in patients with angina? Arch Intern Med. 2002;162:1388–1394. - PubMed

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