Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Oct 1;46(10):e513-e514.
doi: 10.1097/RLU.0000000000003652.

Diffuse White Adipose Tissue 18F-FDG Uptake-An Unusual Finding on 18F-FDG PET/CT

Affiliations
Case Reports

Diffuse White Adipose Tissue 18F-FDG Uptake-An Unusual Finding on 18F-FDG PET/CT

Himanshu Bansal et al. Clin Nucl Med. .

Abstract

Brown adipose tissue of cervical, supraclavicular, and paravertebral regions can show increased FDG uptake. But human white adipose tissue (WAT) shows negligible FDG uptake on 18F-FDG PET/CT scan. We present a case of carcinoma cervix treated with concurrent chemoradiation. 18F-FDG PET/CT shows altered biodistribution of FDG with intense FDG uptake throughout the WAT. Later on, patient confirmed taking herbal medication for herpes zoster infection, which could contain corticosteroids, resulting in enhanced WAT uptake of 18F-FDG.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

References

    1. Sathekge M, Maes A, Kgomo M, et al. Evaluation of glucose uptake by skeletal muscle tissue and subcutaneous fat in HIV-infected patients with and without lipodystrophy using FDG-PET. Nucl Med Commun . 2010;31:311–314.
    1. Hwang DY, Lee JW, Lee SM, et al. Causes of 18 F-FDG uptake on white adipose tissue. Hell J Nucl Med . 2016;19:7–9.
    1. Kong MC, Nadel HR. 18 F-FDG PET/CT with diffusely high FDG uptake throughout subcutaneous adipose tissues. Clin Nucl Med . 2018;43:762–763.
    1. Pattison DA, Hofman MS, Lau E, et al. Enhanced white adipose tissue metabolism in iatrogenic Cushing’s syndrome with FDG PET/CT. J Clin Endocrinol Metab . 2014;99:3041–3042.
    1. Hofman MS, Hicks RJ. White fat et al. Factitious hyperglycemia, and the role of FDG PET to enhance understanding of adipocyte metabolism. EJNMMI Res . 2011;1:1–5.

Publication types

MeSH terms

Substances

LinkOut - more resources