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. 2021 Mar 26:12:658205.
doi: 10.3389/fpsyt.2021.658205. eCollection 2021.

Associations Between Childhood Trauma and the Age of First-Time Drug Use in Methamphetamine-Dependent Patients

Cui Huang  1   2   3 , Qiuyu Yuan  1   2   3 , Ling Zhang  1   2   3 , Lei Wang  1   2   3 , Shu Cui  1   2   3 , Kai Zhang  1   2   3 , Xiaoqin Zhou  1   2   3
Affiliations

Associations Between Childhood Trauma and the Age of First-Time Drug Use in Methamphetamine-Dependent Patients

Cui Huang et al. Front Psychiatry. .

Abstract

Childhood trauma is related to substance use disorder; however, few studies have examined the relationship between childhood trauma and the age at which the drug was first used. The aim of this study was to investigate the relationship between childhood trauma and the age of first-time drug use among methamphetamine-dependent patients. Moreover, we analyzed the characteristics of adverse family environment associated with severe childhood trauma and the risk factors for starting drugs in minors. A baseline interview was conducted with 110 participants who were in detoxification, including demographic information, past substance use, and age of first-time drug use. The participants' childhood trauma experience before 18 years of age was evaluated using the simplified version of the Childhood Trauma Questionnaire (CTQ-SF). The Chinese version of the Family Environment Scale (FES-CV) was used to assess the family environment of methamphetamine-dependent patients. Among 110 non-injecting methamphetamine-dependent patients, nearly half (n = 48, 43.6%) had moderate and severe childhood trauma. Correlation analysis showed that the age of first-time drug use negatively correlated with emotional abuse (r = -0.32, p < 0.01) and physical abuse (r = -0.27, p < 0.01). The age of first-time drug use negatively correlated with conflict (r = -0.20, p < 0.05) and independence (r = -0.22, p < 0.05) of family environment, but positively correlated with intellectual-cultural orientation (r = 0.28, p < 0.01). Additionally, childhood trauma factors significantly correlated with many indexes of family environment, especially cohesion (r = -0.45, p < 0.01), conflict (r = 0.49, p < 0.01), and independence (r = 0.33, p < 0.01). Additionally, the regression model showed that when emotional abuse increased by one point, the age of first-time drug use was 0.69 years earlier. These findings suggest that a detrimental family environment can aggravate childhood trauma, and the experience of childhood emotional or physical abuse may be an effective predictor of early drug use among methamphetamine-dependent patients.

Keywords: age of first-time drug use; childhood trauma; family environment; methamphetamine; minor.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
CONSORT flow diagram.
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References

    1. World Drug Report 2020 . (2020). Available online at: https://wdr.unodc.org/wdr2020/field/WDR20_Booklet_2.pdf (accessed January 10, 2020).
    1. Drug Situation Report in 2019. (2020). Available online at: http://www.gov.cn/xinwen/2020-06/28/content_5522443.htm (accessed January 10, 2020).
    1. Wang Z, Du J, Sun H, Wu H, Xiao Z, Zhao M. Patterns of childhood trauma and psychological distress among injecting heroin users in China. PLoS ONE. (2010) 5:e15882. 10.1371/journal.pone.0015882 - DOI - PMC - PubMed
    1. Marshall BD, Galea S, Wood E, Kerr T. Longitudinal associations between types of childhood trauma and suicidal behavior among substance users: a cohort study. Am J Public Health. (2013) 103:e69–75. 10.2105/AJPH.2013.301257 - DOI - PMC - PubMed
    1. The global burden of disease attributable to alcohol and drug use in 195 countries and territories 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 . Lancet Psychiatry. (2018) 5:987–1012. 10.1016/S2215-0366(18)30337-7 - DOI - PMC - PubMed

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