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. 2021 Mar 31:12:609470.
doi: 10.3389/fendo.2021.609470. eCollection 2021.

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

Affiliations

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

Salvatore Corrao et al. Front Endocrinol (Lausanne). .

Abstract

The pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has involved more than one hundred million individuals, including more than two million deaths. Diabetes represents one of the most prevalent chronic conditions worldwide and significantly increases the risk of hospitalization and death in COVID-19 patients. In this review, we discuss the prevalence, the pathophysiological mechanisms, and the outcomes of COVID-19 infection in people with diabetes. We propose a rationale for using drugs prescribed in patients with diabetes and some pragmatic clinical recommendations to deal with COVID-19 in this kind of patient.

Keywords: COVID-19; SARS-CoV-2; chronic conditions; coronavirus; diabetes; review.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. . A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med (2020) 382(8):727–33. 10.1056/NEJMoa2001017 - DOI - PMC - PubMed
    1. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. . Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus- Infected Pneumonia. N Engl J Med (2020) 382(13):1199–207. 10.1056/NEJMoa2001316 - DOI - PMC - PubMed
    1. World Health Organization Director-General’s Opening Remarks at the Media Briefing on COVID-19–11 (2020).
    1. Lenti MV, Corazza GR, Di Sabatino A. Carving out a place for internal medicine during COVID-19 epidemic in Italy. J Internal Med (2020) 288(2):263–5. 10.1111/joim.13079 - DOI - PMC - PubMed
    1. Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. . Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. Diabetes Res Clin Pract (2019) 157:107843. 10.1016/j.diabres.2019.107843 - DOI - PubMed

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