The "Hygiene Hypothesis" and the Lessons Learnt From Farm Studies
- PMID: 33868259
- PMCID: PMC8044987
- DOI: 10.3389/fimmu.2021.635522
The "Hygiene Hypothesis" and the Lessons Learnt From Farm Studies
Keywords: allergy; asthma; children; epidemiology; immunology.
Conflict of interest statement
Personal fees from Pharmaventures, OM Pharma S. A., Peptinnovate Ltd., Böhringer Ingelheim International GmbH. Patent LU101064: Barn dust extract for the prevention and treatment of diseases pending, Patent EP2361632: Specific environmental bacteria for the protection from and/or the treatment of allergic, chronic inflammatory and/or autoimmune disorders with royalties paid to ProtectImmun GmbH, Patent EP 1411977: Composition containing bacterial antigens used for the prophylaxis and the treatment of allergic diseases. licensed to ProtectImmun GmbH, Patent EP1637147: Stable dust extract for allergy protection licensed to ProtectImmun GmbH, Patent EP 1964570: Pharmaceutical compound to protect against allergies and inflammatory diseases licensed to ProtectImmun GmbH.
Similar articles
-
[Cat, dog, cattle... and allergy].Rev Mal Respir. 2004 Nov;21(5 Pt 1):891-5. doi: 10.1016/s0761-8425(04)71468-0. Rev Mal Respir. 2004. PMID: 15622333 Review. French. No abstract available.
-
Microbiome: Puppy power.Nature. 2017 Mar 29;543(7647):S48-S49. doi: 10.1038/543S48a. Nature. 2017. PMID: 28355190 No abstract available.
-
[The role of the microbial environment for the development of childhood asthma and allergies].Ther Umsch. 2013 Dec;70(12):714-9. doi: 10.1024/0040-5930/a000469. Ther Umsch. 2013. PMID: 24297856 Review. German.
-
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: farm lifestyles and the hygiene hypothesis.Clin Exp Immunol. 2010 Apr;160(1):130-5. doi: 10.1111/j.1365-2249.2010.04138.x. Clin Exp Immunol. 2010. PMID: 20415863 Free PMC article.
-
Early exposure to cats, dogs and farm animals and the risk of childhood asthma and allergy.Pediatr Allergy Immunol. 2020 Apr;31(3):265-272. doi: 10.1111/pai.13186. Epub 2020 Jan 11. Pediatr Allergy Immunol. 2020. PMID: 31829464
Cited by
-
Indoor microbiome and allergic diseases: From theoretical advances to prevention strategies.Eco Environ Health. 2022 Oct 17;1(3):133-146. doi: 10.1016/j.eehl.2022.09.002. eCollection 2022 Sep. Eco Environ Health. 2022. PMID: 38075599 Free PMC article. Review.
-
Respiratory and Intestinal Microbiota in Pediatric Lung Diseases-Current Evidence of the Gut-Lung Axis.Int J Mol Sci. 2022 Jun 18;23(12):6791. doi: 10.3390/ijms23126791. Int J Mol Sci. 2022. PMID: 35743234 Free PMC article. Review.
-
Wheezing-Related Relevant Factors and the Role of Viral Bronchiolitis.Front Allergy. 2021 Oct 5;2:726972. doi: 10.3389/falgy.2021.726972. eCollection 2021. Front Allergy. 2021. PMID: 35387057 Free PMC article. Review.
-
Association of infant antibiotic exposure and risk of childhood asthma: A meta-analysis.World Allergy Organ J. 2021 Dec 6;14(11):100607. doi: 10.1016/j.waojou.2021.100607. eCollection 2021 Nov. World Allergy Organ J. 2021. PMID: 34934469 Free PMC article.
-
The changing epidemiology of paediatric childhood asthma and allergy in different regions of the world.Front Allergy. 2025 Apr 30;6:1584928. doi: 10.3389/falgy.2025.1584928. eCollection 2025. Front Allergy. 2025. PMID: 40370529 Free PMC article. Review.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical