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Case Reports
. 1988 Jul;38(7):1153-5.
doi: 10.1212/wnl.38.7.1153.

Malignant monophasic multiple sclerosis or "Marburg's disease"

M F Mendez  1 , S Pogacar
Affiliations
Case Reports

Malignant monophasic multiple sclerosis or "Marburg's disease"

M F Mendez et al. Neurology. 1988 Jul.

Abstract

We report a patient with an acute monophasic demyelinating disease leading to death 29 days after onset. Neuroimaging showed progressive white matter attenuation, and neuropathology was characteristic of multiple sclerosis. Death in acute MS of the Marburg type may result from severe disseminated demyelination or involvement of critical brainstem structures.

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