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. 2021 Mar 14;13(3):e13883.
doi: 10.7759/cureus.13883.

Diagnostic Accuracy of the Electrocardiography Criteria for Left Ventricular Hypertrophy (Cornell Voltage Criteria, Sokolow-Lyon Index, Romhilt-Estes, and Peguero-Lo Presti Criteria) Compared to Transthoracic Echocardiography

Affiliations

Diagnostic Accuracy of the Electrocardiography Criteria for Left Ventricular Hypertrophy (Cornell Voltage Criteria, Sokolow-Lyon Index, Romhilt-Estes, and Peguero-Lo Presti Criteria) Compared to Transthoracic Echocardiography

Nurseli Bayram et al. Cureus. .

Abstract

Objective/aim: We aimed to evaluate the diagnostic utility of the widely used left ventricular hypertrophy (LVH) electrocardiography (ECG) criteria (Cornell Voltage Criteria [CVC], Sokolow-Lyon Index [SLI], Romhilt-Estes [REC], and Peguero-Lo Presti [PLP] Criteria) compared with the left ventricular mass measured by echocardiography.

Methods: In this prospective diagnostic accuracy study, we screened all consecutive adults (18 to 65 years) who presented to our academic emergency department (ED) with increased blood pressure (≥130/85 mmHg) between January 2016 and January 2017, and we enrolled a convenience sample of 165 patients in our study. The attending emergency physician managed all patients as per their primary complaint. The consulting cardiologist performed a transthoracic echocardiogram (TTE) of the patient and calculated the left ventricular mass (LVM) according to the American Society of Echocardiography (ASE) formula. After completing the patient recruitment phase, researchers evaluated all ECGs and calculated scores for SLI, CVC, REC, and PLP. We used contingency tables to calculate the diagnostic utility metrics of all ECG criteria.

Results: The prevalence of LVH by TTE was 31.5%. CVC, SLI, REC, and PLP criteria correctly identified (true positive rate) abnormal LVM in only 3.9%, 1.9%, 9.6%, and 19.2% of the patients, respectively. CVC, SLI, REC score and PLP criteria performed poorly with extremely low sensitivities (3.9%, 1.9%, 10%, 19.2%) and poor accuracies (67.3%, 64.9%, 57.7%, 69.7%).

Conclusion: ECG voltage criteria's clinical utility in estimating LVM and LVH is low, and it should not be used for this purpose.

Keywords: cornell voltage index; echocardiography; electrocardiography; left ventricular hypertrophy; peguero-lo presti criteria; romhilt-estes score system; sokolow-lyon index.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Validity of electrocardiographic classification of left ventricular hypertrophy across adult ethnic groups with echocardiography as a standard. Vanezis AP, Bhopal R. J Electrocardiol. 2008;41:404–412. - PubMed
    1. Left ventricular hypertrophy by electrocardiogram. Prevalence, incidence, and mortality in the Framingham study. Kannel WB, Gordon T, Offutt D. Ann Intern Med. 1969;71:89–105. - PubMed
    1. Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease. The Framingham study. Kannel WB, Gordon T, Castelli WP, Margolis JR. Ann Intern Med. 1970;72:813–822. - PubMed
    1. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. Haider AW, Larson MG, Benjamin EJ, Levy D. J Am Coll Cardiol. 1998;32:1454–1459. - PubMed
    1. Prognostic value of a new electrocardiographic method for diagnosis of left ventricular hypertrophy in essential hypertension. Verdecchia P, Schillaci G, Borgioni C, et al. J Am Coll Cardiol. 1998;31:383–390. - PubMed

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