Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar 3;8(3):002280.
doi: 10.12890/2021_002280. eCollection 2021.

Acute Epiglottitis Due to COVID-19 Infection

Affiliations

Acute Epiglottitis Due to COVID-19 Infection

Jonathan Emberey et al. Eur J Case Rep Intern Med. .

Abstract

A 53-year-old man presented acutely to the Accident and Emergency department with a 2-day history of progressive odynophagia and shortness of breath. The patient had stridor at rest and acute epiglottitis was suspected. The patient was transferred urgently to theatre for intubation but due to a severely oedematous airway, this was unsuccessful and emergency tracheotomy was performed by the ENT team. Throughout admission the only positive microbiological sample was a nasopharyngeal swab for SARS-CoV-2 infection. In the absence of other positive microbiology, it is highly likely that COVID-19 was the aetiological cause of acute epiglottitis in this instance.

Learning points: COVID-19 infection is a novel disease with multiple presentations; it should be considered as a possible causative organism in patients presenting with acute epiglottitis.Due to the time delay in taking samples for microbiology and results being available, treatment should be commenced with antibiotics, nebulised adrenaline and steroids to cover bacterial infection.Presentation can occur following a delayed inflammatory response and treatment should target the organ system involved.

Keywords: COVID-19; Epiglottitis.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interests: The Authors declare that there are no competing interests.

Figures

Figure 1
Figure 1
Resolving epiglottic oedema and arytenoid cartilage on day 8 after acute upper airway obstruction
Figure 2
Figure 2
Chest x-ray performed 5 days after emergency tracheotomy, showing tracheostomy tube and clear lung fields

References

    1. Lovato A, de Filippis C. Clinical presentation of COVID-19: a systematic review focusing on upper airway symptoms. Ear Nose Throat J. 2020;99(9):569–576. - PubMed
    1. Durand M, Deschler D. Epiglottitis, acute laryngitis, and croup. Infections of the Ears, Nose, Throat, and Sinuses. 2018;4:247–255.
    1. Orhan I, Aydin S, Karlidag T. Infectious and noninfectious causes of epiglottitis in adults, review of 24 patients. Turk Arch Otorhinolaryngol. 2015;53(1):10–14. - PMC - PubMed
    1. Fondaw A, Arshad M, Batool S, Robinson B, Patel T. COVID-19 infection presenting with acute epiglottitis. J Surg Case Rep. 2020;2020(9):rjaa280. - PMC - PubMed
    1. Yanuck S, Pizzorno J, Messier H, Fitzgerald K. Evidence supporting a phased immuno-physiological approach to COVID-19 from prevention through recovery. ICMJ. 2020;19(Suppl 1):8–35. - PMC - PubMed

LinkOut - more resources