Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Apr 6;9(10):2380-2385.
doi: 10.12998/wjcc.v9.i10.2380.

Solitary bone plasmacytoma of the upper cervical spine: A case report

Ren-Jie Li  1 , Xue-Feng Li  1 , Wei-Min Jiang  2
Affiliations
Case Reports

Solitary bone plasmacytoma of the upper cervical spine: A case report

Ren-Jie Li et al. World J Clin Cases. .

Abstract

Background: Solitary bone plasmacytoma (SBP) of the upper cervical spine is a rare diagnosis. The exact role of surgery for SBP remains unclear.

Case summary: We present the first case of SBP of the C2. A 69-year-old Chinese woman presented with severe neck pain and limitation of rotative activity for 2 mo. She underwent anterior one-stage debridement combined with cement augmentation in the C2 to reconstruct stability of the spine. The patient did not receive postoperative radiotherapy. She now remains disease free with no neck pain or neurological deficit after follow-up of 3 years.

Conclusion: Anterior one-stage debridement combined with cement augmentation of the upper cervical spine may be an alternative treatment for SBP.

Keywords: Case report; Cervical spine; Mini-invasive surgery; Multiple myeloma; Solitary bone plasmacytoma; Surgical treatment.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: The authors declare no conflicts of interest involved.

Figures

Figure 1
Figure 1
Laboratory examinations. A and B: C2 biopsy showed multilobe mature plasma cells with no histological pathologies; C: No tumor cells were found in the bone marrow 1 year postoperatively.
Figure 2
Figure 2
Sagittal X-ray. A: Mild cervical kyphosis and cystic lesions in the C2; B and C: Sagittal and plain computed tomography scan revealed bone destruction in the pedicle of C2. The posterior wall of the vertebrae was destroyed.
Figure 3
Figure 3
Magnetic resonance imaging. A: A high signal mass on the right side of C2 with an irregular boundary; B: Cervical disc herniation could be found in C4-6, while no garrulous blade or swollen discs were observed toward the spinal cord in C2.
Figure 4
Figure 4
Single photon emission computed tomography/computed tomography showed high bright signal in the C2 and teeth.
Figure 5
Figure 5
Postoperative X-rays and computed tomography showed that the bone cement filled well, and no leakage occurred during 3 years of follow-up. A and B: The anteroposterior and lateral X-ray was taken at 2 d after surgery; C and D: The two sagittal computed tomography scans were taken at 6 mo and 3 yr after surgery. They showed that no leakage of the bone cement occurred, and the shape of the C2 was maintained.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Cawley DT, Butler JS, Benton A, Altaf F, Rezajooi K, Kyriakou C, Selvadurai S, Molloy S. Managing the cervical spine in multiple myeloma patients. Hematol Oncol. 2019;37:129–135. - PubMed
    1. Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D Working Group of the UK Myeloma Forum; British Committee for Standards in Haematology; British Society for Haematology. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Clin Oncol (R Coll Radiol) 2004;16:405–413. - PubMed
    1. von der Hoeh NH, Tschoeke SK, Gulow J, Voelker A, Siebolts U, Heyde CE. Total spondylectomy for solitary bone plasmacytoma of the lumbar spine in a young woman: a case report and review of literature. Eur Spine J. 2014;23:35–39. - PMC - PubMed
    1. Molloy S, Kyriakou C. Expert's comment concerning Grand Rounds case entitled "total spondylectomy for solitary bone plasmacytoma of the lumbar spine in a young woman. A case report and review of the literature" (by N. von der Hoeh, S.K. Tschoeke, J. Gulow, A. Voelker, U. Siebolts and C.-E. Heyde) Eur Spine J. 2014;23:40–42. - PMC - PubMed
    1. Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ, Mohiuddin M, Young B. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet. 2005;366:643–648. - PubMed

Publication types