Shigella conjugate vaccine efficacy trial in controlled human model and potential immune correlates of protection
- PMID: 33873142
- PMCID: PMC8082079
- DOI: 10.1016/j.ebiom.2021.103343
Shigella conjugate vaccine efficacy trial in controlled human model and potential immune correlates of protection
Conflict of interest statement
Declaration of Competing Interest The authors declare no conflicts of interest.
Comment on
-
Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine.EBioMedicine. 2021 Apr;66:103308. doi: 10.1016/j.ebiom.2021.103308. Epub 2021 Apr 1. EBioMedicine. 2021. PMID: 33813141 Free PMC article.
-
Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection.EBioMedicine. 2021 Apr;66:103310. doi: 10.1016/j.ebiom.2021.103310. Epub 2021 Apr 13. EBioMedicine. 2021. PMID: 33862589 Free PMC article. Clinical Trial.
References
-
- Khalil IA, Troeger C, Blacker BF, Rao PC, Brown A, Atherly DE, Brewer TG, Engmann CM, Houpt ER, Kang G, Kotloff KL, Levine MM, Luby SP, MacLennan CA, Pan WK, Pavlinac PB, Platts-Mills JA, Qadri F, Riddle MS, Ryan ET, Shoultz DA, Steele AD, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC., Jr. Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016. Lancet Infect Dis. 2018 Nov;18(11):1229–1240. - PMC - PubMed
-
- Talaat KR, Alaimo C, Martin P, Bourgeois AL, Dreyer AM, Kaminski RW, Porter CK, Chakraborty S, Clarkson KA, Brubaker J, Elwood D, Frölich R, DeNearing B, Weerts HP, Feijoo B, Halpern J, Sack D, Riddle MS, and Fonck VG. Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection. E Bio Med. (in press) - PMC - PubMed
-
- Clarkson KA, Talaat KR, Alaimo C, Martin P, Bourgeois AL, Dreyer A, Porter CK, Chakraborty S, Brubaker J, Elwood D, Frölich R, DeNearing B, Weerts HP, Feijoo B, Halpern J, Sack D, Riddle MS, Fonck VG and Kaminski RW. Immune response characterization in a human challenge study with a Shigella flexneri 2a Bioconjugate Vaccine. E Bio Med. (in press) - PMC - PubMed
-
- Porter CK, Lynen A, Riddle MS, Talaat K, Sack D, Gutiérrez RL, McKenzie R, DeNearing B, Feijoo B, Kaminski RW, Taylor DN, Kirkpatrick BD, Bourgeois AL. Clinical endpoints in the controlled human challenge model for Shigella: a call for standardization and the development of a disease severity score. PLoS One. 2018 Mar 28;13(3) - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
