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Review
. 2003 Aug;159(2):331-340.
doi: 10.1046/j.1469-8137.2003.00788.x.

Chlamydomonas reinhardtii as a eukaryotic photosynthetic model for studies of heavy metal homeostasis and tolerance

M Hanikenne  1
Affiliations
Free article
Review

Chlamydomonas reinhardtii as a eukaryotic photosynthetic model for studies of heavy metal homeostasis and tolerance

M Hanikenne. New Phytol. 2003 Aug.
Free article

Abstract

The green alga Chlamydomonas reinhardtii is a useful model of a photosynthetic cell. This unicellular eukaryote has been intensively used for studies of a number of physiological processes such as photosynthesis, respiration, nitrogen assimilation, flagella motility and basal body function. Its easy-to-manipulate and short life cycle make this organism a powerful tool for genetic analysis. Over the past 15 yr, a dramatically increased number of molecular technologies (including nuclear and organellar transformation systems, cosmid, yeast artificial chromosome (YAC) and bacterial artificial chromosome (BAC) libraries, reporter genes, RNA interference, DNA microarrays, etc.) have been applied to Chlamydomonas. Moreover, as parts of the Chlamydomonas genome project, molecular mapping, as well as whole genome and extended expressed sequence tag (EST) sequencing programs, are currently underway. These developments have allowed Chlamydomonas to become an extremely valuable model for molecular approaches to heavy metal homeostasis and tolerance in photosynthetic organisms.

Keywords: Chlamydomonas; cadmium (Cd); copper (Cu); heavy metal homeostasis; heavy metal tolerance; iron (Fe).

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References

    1. Adam M, Lentz KE, Loppes R. 1993. Insertional mutagenesis to isolate acetate-requiring mutants in Chlamydomonas reinhardtii. FEMS Microbiology Letters 110: 265-268.
    1. Asamizu E, Miura K, Kucho K, Inoue Y, Fukuzawa H, Ohyama K, Nakamura Y, Tabata S. 2000. Generation of expressed sequence tags from low-CO2 and high-CO2 adapted cells of Chlamydomonas reinhardtii. DNA Research 7: 305-307. - PubMed
    1. Asamizu E, Nakamura Y, Sato S, Fukuzawa H, Tabata S. 1999. A large scale structural analysis of cDNAs in a unicellular green alga, Chlamydomonas reinhardtii. I. Generation of 3433 non-redundant expressed sequence tags. DNA Research 6: 369-373. - PubMed
    1. Askwith C, Kaplan J. 1998. Iron and copper transport in yeast and its relevance to human disease. Trends in Biochemical Science 23: 135-138.
    1. Ben-Bassat D, Shelef G, Gruner N, Shuval HI. 1972. Growth of Chlamydomonas in a medium containing mercury. Nature 240: 43-44. - PubMed

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