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. 1988 Mar;23(3):239-44.
doi: 10.1016/0165-1781(88)90014-5.

Plasma homovanillic acid levels and subtyping of schizophrenia

W H Chang  1 , T Y Chen, C F Lee, J C Hung, W H Hu, E K Yeh
Affiliations

Plasma homovanillic acid levels and subtyping of schizophrenia

W H Chang et al. Psychiatry Res. 1988 Mar.

Abstract

Plasma levels of homovanillic acid (HVA), a major metabolite of dopamine, were measured in a group of 24 schizophrenic inpatients before and during 6 weeks of haloperidol (HAL) treatment. Steady-state plasma HAL levels were measured in parallel with plasma HVA. Differential plasma HVA responses to HAL treatment were found between good and poor outcome patients. The two groups did not differ significantly in plasma HAL levels. Two hypothetical subtypes of schizophrenia are proposed.

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