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. 2021 Apr 18;14(4):510-516.
doi: 10.18240/ijo.2021.04.05. eCollection 2021.

Trabeculectomy with Ologen implant versus perfluoropropane gas bubble for open angle glaucoma in pseudophakic eyes

Ahmed S Elwehidy  1 , Tharwat Mokbel  1 , Hossam Youssef Abouelkheir  1 , Waleed Abou Samra  1 , Faried M Wagdy  2 , Amr Mohammed Elsayed Abdelkader  1
Affiliations

Trabeculectomy with Ologen implant versus perfluoropropane gas bubble for open angle glaucoma in pseudophakic eyes

Ahmed S Elwehidy et al. Int J Ophthalmol. .

Abstract

Aim: To evaluate the safety and efficacy of augmented trabeculotomy with Ologen versus perfluoropropane in management of pseudophakic glaucoma.

Methods: This is a comparative randomized study included 57 pseudophakic eyes of 57 patients with medically uncontrolled open angle glaucoma (OAG). Twenty-nine patients were allocated in group I (trabeculectomy with Ologen; trab-ologen group), while 28 patients were assigned in group II (trabeculectomy with perfluoropropane gas bubble; trab-C3F8 gas bubble group).

Results: The intraocular pressure (IOP) was significantly reduced in both study groups at all postoperative follow up intervals (1wk, 3, 6, 12, 18, 24, 30 and 36mo, P<0.001). The differences between the mean IOP values of both groups remained statistically insignificance during the early 12 months of follow up. However, the trab-ologen group achieved a statistically significant reduction over the trab-C3F8 gas bubble group during the last 24 months of follow up.

Conclusion: Augmentation of trabeculectomy with either Ologen implant or perfluoropropane gas bubble are associated with strict long term IOP control and evident safety in medically-uncontrolled pseudophakic eyes with OAG.

Keywords: Ologen; perfluoropropane; pseudophakic glaucoma; trabeculectomy with Ologen; trabeculectomy with perfluoropropane.

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Figures

Figure 1
Figure 1. Kaplan-Meier survival analysis curve for the probability of postoperative success rate.
See this image and copyright information in PMC

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