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Editorial
. 2021 Apr 20;46(2):E313-E318.
doi: 10.1503/jpn.210036.

Can treatment of obesity reduce depression or vice versa?

Stephanie L Borgland  1
Affiliations
Editorial

Can treatment of obesity reduce depression or vice versa?

Stephanie L Borgland. J Psychiatry Neurosci. .
No abstract available

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Conflict of interest statement

None declared.

Figures

Fig. 1
Fig. 1
Overview of factors that underlie both obesity and depression and that lead to neural circuit changes. HPA = hypothalamic–pituitary–adrenal axis; IL = interleukin, TNF = tumour necrosis factor.
See this image and copyright information in PMC

References

    1. Obesity and overweight. Geneva: World Health Organization. Available: www.who.int/news-room/fact-sheets/detail/obesity-and-overweight (accessed 2021 Feb. 23).
    1. Depression. Geneva: World Health Organization. Available: www.who.int/news-room/fact-sheets/detail/depression (accessed 2021 Feb. 23).
    1. Penninx BW, Beekman AT, Honig A, et al. . Depression and cardiac mortality: results from a community-based longitudinal study. Arch Gen Psychiatry 2001;58:221–7. - PubMed
    1. GBD 2015 Obesity Collaborators, Afshin A, Forouzanfar MH, et al. . Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med 2017;377:13–27. - PMC - PubMed
    1. Luppino FS, de Wit LM, Bouvy PF, et al. . Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 2010;67:220–9. - PubMed

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