Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr;41(2):219-227.
doi: 10.1007/s11596-021-2339-9. Epub 2021 Apr 20.

Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China

Bao-Ying Feng #  1 , Yang Peng #  2 , Jun Liang  3 , Li Wu  1 , Qun-Jiao Jiang  1 , Shun Liu  3 , Xiao-Yun Zeng  3 , Dong-Ping Huang  1 , Xiao-Qiang Qiu  3 , Han Li  4
Affiliations

Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China

Bao-Ying Feng et al. Curr Med Sci. 2021 Apr.

Abstract

Risk factors for adverse pregnancy outcomes among Zhuang ethnic pregnant women are unclear. This study analyzed the incidence and risk factors related to preterm birth (PB), low birth weight (LBW) and macrosomia in Zhuang population. We conducted a prospective cohort study of 9965 Zhuang pregnancy women in Guangxi, China. Information on mothers and newborns was obtained by using questionnaires and referring to medical records. Multivariate logistic regression analyses were used to evaluate the association between related factors and adverse pregnancy outcomes. Our results showed that the incidence of PB, LBW and macrosomia in Zhuang people was 5.55%, 5.64% and 2.19%, respectively. Maternal age ≥36 years (OR=2.22, 95% CI: 1.51-3.27) was related to a higher incidence of PB. Those with pre-pregnancy body mass index (BMI) <18.5 kg/m2 (OR=1.91, 95% CI: 1.45-2.51), and had a female fetus (OR=1.74, 95% CI: 1.36-2.23) were more likely to have LBW infants. Maternal age between 31 and 35 years (OR=1.76, 95% CI: 1.03-2.99) and pre-pregnancy overweight or obesity (OR=1.79, 95% CI: 1.15-2.80) were associated with a higher risk of macrosomia. The protective factors of macrosomia were maternal pre-pregnancy BMI <18.5 kg/m2 (OR=0.30, 95% CI: 0.15-0.60) and female fetus (OR=0.41, 95% CI: 0.28-0.59). Our study provided a reference for maternal and childcare administration among Zhuang population.

Keywords: Zhuang ethnic; cohort study; low birth weight; macrosomia; preterm birth; risk factors.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Blencowe H, Cousens S, Oestergaard MZ, et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet, 2012,379(9832):2162–2172 - PubMed - DOI - PMC
    1. Vogel JP, Chawanpaiboon S, Moller AB, et al. The global epidemiology of preterm birth. Best Pract Res Clin Obstet Gynaecol, 2018,52:3–12 - PubMed - DOI - PMC
    1. Evensen KA, Steinshamn S, Tjonna AE, et al. Effects of preterm birth and fetal growth retardation on cardiovascular risk factors in young adulthood. Early Hum Dev, 2009,85(4):239–245 - PubMed - DOI - PMC
    1. Crump C, Sundquist J, Winkleby MA, et al. Gestational age at birth and mortality from infancy into mid-adulthood: a national cohort study. Lancet Child Adolesc Health, 2019,3(6):408–417 - PubMed - PMC - DOI
    1. Li S, Xi B. Preterm birth is associated with risk of essential hypertension in later life. Int J Cardiol, 2014, 172(2):e361–363 - PubMed - DOI - PMC

LinkOut - more resources