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Case Reports
. 2021 Jul;194(1):211-213.
doi: 10.1111/bjh.17471. Epub 2021 Apr 20.

False-positive heparin-PF4 latex immunoturbidimetric assay due to lupus anti-coagulant interference: a case report

Hannah L McRae  1 , Jozal W Moore  2 , Jainulabdeen J Ifthikharuddin  2 , Majed A Refaai  1
Affiliations
Case Reports

False-positive heparin-PF4 latex immunoturbidimetric assay due to lupus anti-coagulant interference: a case report

Hannah L McRae et al. Br J Haematol. 2021 Jul.
No abstract available

Keywords: antiphospholipid syndrome; heparin; heparin induced thrombocytopenia; lupus anticoagulant; thrombocytopenia.

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References

    1. Warkentin TE, Sheppard J-A, Linkins L-A, Arnold DM, Nazy I, et al. Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL® HIT-Ab(PF4-H)] for the diagnosis of immune heparin-induced thrombocytopenia. Thromb Res. 2017;153:108-17.
    1. Refaai MA, Conley G, Ortel TL, Francis JL. Evaluation of a rapid and automated heparin-induced thrombocytopenia immunoassay. Int J Lab Hematol. 2019;41(4):478-84.
    1. Garcia D, Erkan D. Diagnosis and management of the antiphospholipid syndrome. N Engl J Med. 2018;378(21):2010-21.
    1. Fleetwood T, Cantello R, Comi C. Antiphospholipid syndrome and the neurologist: from pathogenesis to therapy. Front Neurol. 2018;9:1001.
    1. Yelnik CM, et al. Thrombocytopenia in primary antiphospholipid syndrome, a marker of high-risk patients? Eur J Intern Med. 2020;74:106-7.

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