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Review
. 2021 Jan-Mar;25(1):e2020.00081.
doi: 10.4293/JSLS.2020.00081.

Port-Site Metastasis in Gynecological Malignancies

Kelly Benabou  1 , Wafa Khadraoui  1 , Tarek Khader  2 , Pei Hui  3 , Rodrigo Fernandez  1 , Masoud Azodi  2 , Gulden Menderes  2
Affiliations
Review

Port-Site Metastasis in Gynecological Malignancies

Kelly Benabou et al. JSLS. 2021 Jan-Mar.

Abstract

Background: Minimally invasive oncologic surgery has become the standard of care in many gynecologic cancers. While laparoscopic surgery provides many benefits to patients, such as faster recovery, there are unique challenges associated with minimally invasive techniques. Port-site metastasis is a rare complication after laparoscopic oncologic surgery in management of gynecologic malignancies.

Methods: We present the case of a 44-year-old female with isolated port-site recurrence following laparoscopic radical hysterectomy with node-negative, clinical stage IB1 cervical adenocarcinoma. In addition, we provide an updated review of the literature on management and oncologic outcomes of port-site metastasis.

Conclusion: Port-site metastasis prevention necessitates a better understanding of underlying risk factors and pathophysiology in order to optimize outcomes. Future studies are needed on risk-reducing strategies and standardization of management for port-site metastasis.

Keywords: CO2 insufflation; Cervical cancer; Gynecologic malignancy; Port-site metastasis.

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Conflict of interest statement

Conflict of Interest: none.

Figures

Figure 1.
Figure 1.
Histological features of the primary and recurrent tumors. A: Low-power view of the primary cervical adenocarcinoma of usual type, deeply invading the uterine stroma (hematoxylin and eosin 20x). B: High-power view of the carcinoma showing typical cribriform adenocarcinoma glands (hematoxylin and eosin 100x). C: Recurrent tumor at Low-power magnification showing similar growth patterns (hematoxylin and eosin 20x). D: High-power view of the recurrent tumor showing similar histological features to the primary cervical tumor (hematoxylin and eosin 100x).
Figure 2.
Figure 2.
Pre-operative radiographic studies of port-site metastasis. A: Magnetic resonance imaging of abdomen and pelvis with and without intravenous contrast in 2016. T1- and T2-Weighted axial images demonstrating diffusely enhancing mass measuring 2.0 × 4.1 × 3.1 centimeters, involving the right rectus sheath. B: computed tomography of abdomen and pelvic with intravenous contrast and oral contrast showing 1.7 centimeter right abdominal wall metastatic implant.
See this image and copyright information in PMC

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