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. 2021 Apr 21;47(1):97.
doi: 10.1186/s13052-021-01013-8.

Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases

Marzia Duse #  1 , Francesca Santamaria #  2 , Maria Carmen Verga  3 , Marcello Bergamini  4 , Giovanni Simeone  5 , Lucia Leonardi  6 , Giovanna Tezza  7 , Annamaria Bianchi  8 , Annalisa Capuano  9 , Fabio Cardinale  10 , Giovanni Cerimoniale  11 , Massimo Landi  12 , Monica Malventano  4 , Mariangela Tosca  13 , Attilio Varricchio  14 , Anna Maria Zicari  15 , Carlo Alfaro  16 , Salvatore Barberi  17 , Paolo Becherucci  18 , Roberto Bernardini  19 , Paolo Biasci  20 , Carlo Caffarelli  21 , Valeria Caldarelli  22 , Carlo Capristo  23 , Serenella Castronuovo  24 , Elena Chiappini  25   26 , Renato Cutrera  27 , Giovanna De Castro  15 , Luca De Franciscis  28 , Fabio Decimo  23 , Iride Dello Iacono  29 , Lucia Diaferio  30 , Maria Elisa Di Cicco  31 , Caterina Di Mauro  32 , Cristina Di Mauro  9 , Dora Di Mauro  33 , Francesco Di Mauro  34 , Gabriella Di Mauro  9 , Mattia Doria  35 , Raffaele Falsaperla  36 , Valentina Ferraro  37 , Vassilios Fanos  38 , Elena Galli  39 , Daniele Giovanni Ghiglioni  40 , Luciana Indinnimeo  1 , Ahmad Kantar  41 , Adima Lamborghini  42 , Amelia Licari  43 , Riccardo Lubrano  44 , Stefano Luciani  45 , Francesco Macrì  46 , Gianluigi Marseglia  43 , Alberto Giuseppe Martelli  47 , Luigi Masini  48 , Fabio Midulla  6 , Domenico Minasi  49 , Vito Leonardo Miniello  50 , Michele Miraglia Del Giudice  23 , Sergio Renzo Morandini  11 , Germana Nardini  51 , Agostino Nocerino  52 , Elio Novembre  53 , Giovanni Battista Pajno  54 , Francesco Paravati  55 , Giorgio Piacentini  56 , Cristina Piersantelli  57 , Gabriella Pozzobon  58 , Giampaolo Ricci  59 , Valter Spanevello  60 , Renato Turra  61 , Stefania Zanconato  62 , Melissa Borrelli  63 , Alberto Villani  64 , Giovanni Corsello  65 , Giuseppe Di Mauro  34 , Diego Peroni  66
Affiliations

Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases

Marzia Duse et al. Ital J Pediatr. .

Erratum in

  • Correction: Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases.
    Duse M, Santamaria F, Verga MC, Bergamini M, Simeone G, Leonardi L, Tezza G, Bianchi A, Capuano A, Cardinale F, Cerimoniale G, Landi M, Malventano M, Tosca M, Varricchio A, Zicari AM, Alfaro C, Barberi S, Becherucci P, Bernardini R, Biasci P, Caffarelli C, Caldarelli V, Capristo C, Castronuovo S, Chiappini E, Cutrera R, De Castro G, De Franciscis L, Decimo F, Iacono ID, Diaferio L, Di Cicco ME, Di Mauro C, Di Mauro C, Di Mauro D, Di Mauro F, Di Mauro G, Doria M, Falsaperla R, Ferraro V, Fanos V, Galli E, Ghiglioni DG, Indinnimeo L, Kantar A, Lamborghini A, Licari A, Lubrano R, Luciani S, Macrì F, Marseglia G, Martelli AG, Masini L, Midulla F, Minasi D, Miniello VL, Del Giudice MM, Morandini SR, Nardini G, Nocerino A, Novembre E, Pajno GB, Paravati F, Piacentini G, Piersantelli C, Pozzobon G, Ricci G, Spanevello V, Turra R, Zanconato S, Borrelli M, Villani A, Corsello G, Di Mauro G, Peroni D. Duse M, et al. Ital J Pediatr. 2022 Feb 25;48(1):35. doi: 10.1186/s13052-022-01231-8. Ital J Pediatr. 2022. PMID: 35216620 Free PMC article. No abstract available.

Abstract

Background: In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infectious diseases, and ear, nose, and throat medicine.

Methods: Clinical questions identifying Population, Intervention(s), Comparison and Outcome(s) were addressed by methodologists and a general agreement on the topics and the strength of the recommendations (according to the GRADE system) was obtained following the Delphi method. The literature selection included secondary sources such as evidence-based guidelines and systematic reviews and was integrated with primary studies subsequently published.

Results: The expert panel provided a number of recommendations on the use of inhaled corticosteroids in preschool wheezing, bronchial asthma, allergic and non-allergic rhinitis, acute and chronic rhinosinusitis, adenoid hypertrophy, laryngitis and laryngospasm.

Conclusions: We provided a multidisciplinary update on the current recommendations for the management and prevention of the most common paediatric airways disorders requiring inhaled corticosteroids, in order to share useful indications, identify gaps in knowledge and drive future research.

Keywords: Adenoid hypertrophy; Asthma; Inhaled corticosteroids; Laryngospasm; Laryngotracheitis; Rhinitis; Rhinosinusitis; Wheezing.

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Conflict of interest statement

All authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Inhaled corticosteroids currently available
Fig. 2
Fig. 2
“Pulmonary” bioavailability and “oral” bioavailability of inhaled corticosteroids
See this image and copyright information in PMC

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