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Randomized Controlled Trial
. 2021 Oct;75(10):1001-1009.
doi: 10.1136/jech-2020-216219. Epub 2021 Apr 21.

Effectiveness of a motivational intervention based on spirometry results to achieve smoking cessation in primary healthcare patients: randomised, parallel, controlled multicentre study

Francisco Martin-Lujan  1   2   3 , Josep Basora-Gallisa  2   3 , Felipe Villalobos  2 , Nuria Martin-Vergara  2 , Estefania Aparicio-Llopis  3 , Irene Pascual-Palacios  4 , Antoni Santigosa-Ayala  2   3   5 , Roxana-Elena Catalin  2   6 , Cristina Rey-Reñones  2   3 , Rosa Solà  7   8   9 ; ESPITAP Study Group Investigators
Collaborators, Affiliations
Randomized Controlled Trial

Effectiveness of a motivational intervention based on spirometry results to achieve smoking cessation in primary healthcare patients: randomised, parallel, controlled multicentre study

Francisco Martin-Lujan et al. J Epidemiol Community Health. 2021 Oct.

Abstract

Objective: This 12-month study in a primary healthcare network aimed to assess the effectiveness of usual smoking cessation advice compared with personalised information about the spirometry results.

Design: Randomised, parallel, controlled, multicentre clinical trial.

Setting: This study involved 12 primary healthcare centres (Tarragona, Spain).

Participants: Active smokers aged 35-70 years, without known respiratory disease. Each participant received brief smoking cessation advice along with a spirometry assessment. Participants with normal results were randomised to the intervention group (IG), including detailed spirometry information at baseline and 6-month follow-up or control group (CG), which was simply informed that their spirometry values were within normal parameters.

Main outcome: Prolonged abstinence (12 months) validated by expired-CO testing.

Results: Spirometry was normal in 571 patients in 571 patients (45.9% male), 286 allocated to IG and 285 to CG. Baseline characteristics were comparable between the groups. Mean age was 49.8 (SD ±7.78) years and mean cumulative smoking exposure was 29.2 (±18.7) pack-years. Prolonged abstinence was 5.6% (16/286) in the IG, compared with 2.1% (6/285) in the CG (p=0.03); the cumulative abstinence curve was favourable in the IG (HR 1.98; 95% CI 1.29 to 3.04).

Conclusions: In active smokers without known respiratory disease, brief advice plus detailed spirometry information doubled prolonged abstinence rates, compared with brief advice alone, in 12-month follow-up, suggesting a more effective intervention to achieve smoking cessation in primary healthcare.

Trial registration number: NCT01194596.

Keywords: epidemiology; public health; smoking.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Screening, randomisation and follow-up of the participants (CONSORT diagram). CONSORT, Consolidated Standards of Reporting Trials.
Figure 2
Figure 2
Cumulative incidence rates of tobacco abandonment at 12-month follow-up in the intervention group and control group (analysis from Cox regression models).
See this image and copyright information in PMC

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