Single dose prostate radiotherapy - a step too far?
- PMID: 33883723
- DOI: 10.1038/s41585-021-00468-y
Single dose prostate radiotherapy - a step too far?
Comment on
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Safety and Efficacy of Virtual Prostatectomy With Single-Dose Radiotherapy in Patients With Intermediate-Risk Prostate Cancer: Results From the PROSINT Phase 2 Randomized Clinical Trial.JAMA Oncol. 2021 May 1;7(5):700-708. doi: 10.1001/jamaoncol.2021.0039. JAMA Oncol. 2021. PMID: 33704378 Free PMC article. Clinical Trial.
References
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- Dearnaley, D. et al. Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial. Lancet Oncol. 17, 1047–1060 (2016). - DOI
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- Brand, D. H. et al. Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity results from an international, randomised open-label, phase 3, non-inferiority trial. Lancet Oncol. 20, 1531–1543 (2019). - DOI
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- Widmark, A. et al. Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial. Lancet 394, 385–395 (2019). - DOI
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- Greco, C. et al. Safety and efficacy of virtual prostatectomy with single-dose radiotherapy in patients with intermediate-risk prostate cancer: results from the PROSINT phase 2 randomized clinical trial. JAMA Oncol. https://doi.org/10.1001/jamaoncol.2021.0039 (2021). - DOI - PubMed
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- Meier, R. M. et al. Multicenter trial of stereotactic body radiation therapy for low- and intermediate-risk prostate cancer: survival and toxicity endpoints. Int. J. Radiat. Oncol. Biol. Phys. 102, 296–303 (2018). - DOI
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