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. 2021 Jan-Dec:26:2515690X211011038.
doi: 10.1177/2515690X211011038.

Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review

Wiraphol Phimarn  1   2 , Bunleu Sungthong  3 , Hiroyuki Itabe  2
Affiliations

Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review

Wiraphol Phimarn et al. J Evid Based Integr Med. 2021 Jan-Dec.

Abstract

Aim: The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed.

Methods: Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors.

Results: Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment.

Conclusions: This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.

Keywords: anthropometry; blood glucose; lipid profile; systematic review; triphala.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
A PRISMA flow diagram describing the selection process for identifying studies included in the systematic review.
Figure 2.
Figure 2.
Risk of bias summary from individual studies (+ = low risk, − = high risk, and? = unclear).
See this image and copyright information in PMC

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