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. 2021 Aug;161(2):715-718.e4.
doi: 10.1053/j.gastro.2021.04.025. Epub 2021 Apr 20.

Serologic Response to Messenger RNA Coronavirus Disease 2019 Vaccines in Inflammatory Bowel Disease Patients Receiving Biologic Therapies

Serre-Yu Wong  1 , Rebekah Dixon  2 , Vicky Martinez Pazos  2 , Sacha Gnjatic  3 , Jean-Frederic Colombel  2 , Ken Cadwell  4 ; ICARUS-IBD Working Group
Collaborators, Affiliations

Serologic Response to Messenger RNA Coronavirus Disease 2019 Vaccines in Inflammatory Bowel Disease Patients Receiving Biologic Therapies

Serre-Yu Wong et al. Gastroenterology. 2021 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Antibody response to SARS-CoV-2 immunization in IBD patients compared with HCW control subjects. (A) Siemens Healthineers SARS-CoV-2 Total (COV2T) and SARS-CoV-2 IgG (sCOVG) testing for total immunoglobulin and IgG against SARS-CoV-2 RBD. Thresholds for positive tests and maximum index value for COV2T are shown by dotted lines as indicated. The percentage of seropositivity over time since first vaccine dose in IBD patients is shown in the table. (B) Anti-S IgG results comparing IBD with PICR/HCW cohorts over time.
Supplementary Figure 1
Supplementary Figure 1
Comparison of SARS-CoV-2 antibody measurements in IBD patients after completing 2 doses of Pfizer-BioNTech or NIH-Moderna vaccination by (A) medications and (B) vaccine make. Differences between groups were nonsignificant (P > .05) unless otherwise noted. ∗P ≤ .05, ∗∗P ≤ .01.
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References

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