Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun;99(6):1490-1492.
doi: 10.1016/j.kint.2021.04.009. Epub 2021 Apr 20.

Antibody response to the BNT162b2 vaccine in maintenance hemodialysis patients

Affiliations

Antibody response to the BNT162b2 vaccine in maintenance hemodialysis patients

Philippe Attias et al. Kidney Int. 2021 Jun.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Serologic response after first and second injections of the BNT162b2 mRNA vaccine in patients with or without history of coronavirus disease 2019 (COVID-19). (a) Comparison of the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti–spike antibodies over time (days) after the first (day 0; blue arrow) and second (day 28; red arrow) BNT162b2 mRNA vaccine between a group with previous COVID-19 (n = 13) and a group with no history of COVID-19 (n = 57). Scatterplot with bar is shown. Means ± SEM are shown. The cutoff for negative serology was defined according to the manufacturer (index signal-to-cutoff [S/CO] <1; dashed line). (b). Kinetics of the evolution of SARS-CoV-2 anti–spike antibodies over time (days) with repeated measures matched for each patient, after the first (day 0; blue arrow) and second (day 28; red arrow) BNT162b2 mRNA vaccine between a group with previous COVID-19 (n = 13) and a group with no history of COVID-19 (n = 57). Spaghetti plot is shown. The cutoff for negative serology was defined according to the manufacturer (index S/CO <1; dashed line). Statistical analysis with mixed-effect analysis with Sidak multiple-comparison test. ∗∗P < 0.01, ∗∗∗∗P < 0.0001. NS, nonsignificant.

Comment in

References

    1. Kato S., Chmielewski M., Honda H. Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol. 2008;3:1526–1533. - PMC - PubMed
    1. Dagan N., Barda N., Kepten E. BNT162b2 mRNA Covid-19 vaccine in a nationwide mass vaccination setting. N Engl J Med. 2021;384:1412–1423. - PMC - PubMed
    1. Sakhi H., Dahmane D., Attias P. Kinetics of anti-SARS-CoV-2 IgG antibodies in hemodialysis patients six months after infection [e-pub ahead of print]. J Am Soc Nephrol. https://doi.org/10.1681/ASN.2020111618 Accessed February 26, 2021. - DOI - PMC - PubMed
    1. Prendecki M., Clarke C., Brown J. Effect of previous SARS-CoV-2 infection on humoral and T-cell responses to single-dose BNT162b2 vaccine. Lancet. 2021;397:1178–1181. - PMC - PubMed