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. 2021 Mar 18;15(2):10-15.
doi: 10.21010/ajid.v15i2.3. eCollection 2021.

PREVALENCE OF HUMAN PARVOVIRUS B19 IgG AND IgM ANTIBODIES AMONG PREGNANT WOMEN ATTENDING ANTENATAL CLINIC AT FEDERAL TEACHING HOSPITAL IDO-EKITI, NIGERIA

Richard Yomi Akele  1 , Jennifer Tamuno Abelekum  1 , Bernard Oluwapelumi Oluboyo  1 , Janet Funmilayo Akinseye  1 , Seyi Samson Enitan  2 , Olusola Ayodeji Olayanju  1 , Emmanuel Jide Akele  1
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PREVALENCE OF HUMAN PARVOVIRUS B19 IgG AND IgM ANTIBODIES AMONG PREGNANT WOMEN ATTENDING ANTENATAL CLINIC AT FEDERAL TEACHING HOSPITAL IDO-EKITI, NIGERIA

Richard Yomi Akele et al. Afr J Infect Dis. .

Abstract

Background: Human Parvovirus B19 (B19V) is a DNA virus, transmitted through respiratory secretions, hand-to-mouth-contact, blood transfusion and trans-placental transfer. It causes high mortality and morbidity in pregnant women, thus contributing to poor maternal and child health. B19V has been neglected due to dearth of epidemiological data. The aim of this study was to determine the sero-prevalence of Human Parvovirus B19 antibodies among pregnant women attending antenatal clinic at Federal Teaching Hospital Ido-Ekiti, Nigeria.

Materials and methods: This cross-sectional study enrolled pregnant women attending Federal Teaching Hospital Ido-Ekiti from January to May 2019 to obtain sero-epidemiological data. One hundred and twenty-two (122) consenting pregnant women were enrolled following institutional ethical approval. They were administered structured questionnaire and venous blood was collected in plain tubes for serum extraction. Sera samples were analyzed for IgG and IgM antibodies using the enzyme linked immunosorbent assay method. Percentages, median, chi-square and multivariate analysis were carried out using SPSS version 17.

Results: The prevalence of IgG was 44.3% (54/122), IgM 41.8% (51/122), and IgG/IgM 28.7% (35/122) leaving 55.7% (68/122) of the population uninfected. The median age of participants was 22 (Interquartile range 18-25) years among which 36-45years had the highest prevalence which was not statistically significant (p=0.09 X 2 =4.75). There was association between miscarriage, still birth, history of blood transfusion and prevalence of Human Parvovirus B19 (p<0.05).

Conclusion: There is a high Prevalence of B19V among pregnant women attending antenatal clinic in this study. This underscores the need for testing and immunization of pregnant women against B19V.

Keywords: Antibodies; Human Parvovirus B19; IgG; IgM; Nigeria; Pregnancy; Sero-prevalence.

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Conflict of interest statement

Disclosure of conflict of interest All authors declare no form of conflict of interest in this study.

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References

    1. Abiodun I, Opaleye OO, Ojurongbe O, Fagbami AH. Seroprevalence of Parvovirus B19 IgG and IgM antibodies among pregnant women in Oyo State Nigeria. Journal Infection in Developing Countries. 2013;7:946–950. doi:10.3855/jidc.3157. - PubMed
    1. Akele RY, Agu CC, Oluboyo BO, Akinseye JF, Akele EJ, Itodo EG. Seroprevalence of Bartonella henselae IgG and IgM Antibodies among HIV Infected Individuals attending Heart-To-Heart Clinic at Federal Teaching Hospital Ido-Ekiti, Nigeria. World Journal of Advance Healthcare Research. 2020;4(3):242–248.
    1. Akele RY, Pam BN, Oluboyo BO, Enitan SS, Akinseye JF, Adewumi FA. Seroprevalence of Rubella IgG and IgM Antibodies among Pregnant Women Attending Antenatal Clinic in Federal Teaching Hospital Ido-Ekiti, Nigeria. Asian Journal of Immunology. 2020;4(1):27–35.
    1. Blumel J, Rinckel LA, Lee DC, Roth NJ, Baylis SA. Inactivation and neutralization of ParvovirusB19 genotype 3. Transfusion. 2012;52(7):1490–1497. - PubMed
    1. Bremner JA, Cohen BJ. Parvovirus B19 as a cause of anemia in human immunodeficiency virus-infected patients. Journal of Infectious Diseases. 1994;169:938–940. - PubMed

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