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. 2021 Apr;26(16):2100348.
doi: 10.2807/1560-7917.ES.2021.26.16.2100348.

Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021

Tjede Funk  1 , Anastasia Pharris  1 , Gianfranco Spiteri  1 , Nick Bundle  1 , Angeliki Melidou  1 , Michael Carr  2   3 , Gabriel Gonzalez  2   3 , Alejandro Garcia-Leon  4 , Fiona Crispie  5 , Lois O'Connor  6 , Niamh Murphy  6 , Joël Mossong  7 , Anne Vergison  7 , Anke K Wienecke-Baldacchino  8 , Tamir Abdelrahman  8 , Flavia Riccardo  9 , Paola Stefanelli  9 , Angela Di Martino  9 , Antonino Bella  9 , Alessandra Lo Presti  9 , Pedro Casaca  10 , Joana Moreno  10 , Vítor Borges  11 , Joana Isidro  11 , Rita Ferreira  11 , João Paulo Gomes  11 , Liidia Dotsenko  12 , Heleene Suija  12 , Jevgenia Epstein  12 , Olga Sadikova  12 , Hanna Sepp  12 , Niina Ikonen  13 , Carita Savolainen-Kopra  13 , Soile Blomqvist  13 , Teemu Möttönen  13 , Otto Helve  13 , Joana Gomes-Dias  1 , Cornelia Adlhoch  1 ; COVID study groups  14
Affiliations

Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021

Tjede Funk et al. Euro Surveill. 2021 Apr.

Abstract

We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-19 cases with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0-2.9; B.1.351: 3.6, 95% CI: 2.1-6.2; P.1: 2.6, 95% CI: 1.4-4.8) and B.1.1.7/SGTF and P.1 cases also for intensive care admission (B.1.1.7/SGTF: 2.3, 95% CI: 1.4-3.5; P.1: 2.2, 95% CI: 1.7-2.8).

Keywords: COVID-19; Europe; SARS-CoV-2; surveillance; variants of concern.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure
Figure
Reported SARS-CoV-2 VOC cases, by reporting country and week of reporting, EU/EEA, weeks 38/2020–10/2021 (n = 23,343)
See this image and copyright information in PMC

References

    1. Public Health England (PHE). Investigation of novel SARS-CoV-2 variant - variant of concern 202012/01. London: PHE; 2020. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploa...
    1. European Centre for Disease Prevention and Control (ECDC). Risk assessment: Risk related to spread of new SARS-CoV-2 variants of concern in the EU/EEA - first update. Stockholm: ECDC; 2021. Available from: https://www.ecdc.europa.eu/en/publications-data/covid-19-risk-assessment...
    1. Japanese National Institute of Infectious Diseases (NIID). Brief report: new variant strain of SARS-CoV-2 identified in travelers from Brazil: Tokyo: NIID; 2021. Available from: https://www.niid.go.jp/niid/en/2019-ncov-e/10108-covid19-33-en.html
    1. Faria NR, Claro IM, Candido D, Franco LAM, Andrade PS, Coletti TM, et al. Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings. Virological.org. 2021. Available from: https://virological.org/t/genomic-characterisation-of-an-emergent-sars-c...
    1. Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, et al. Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa. medRxiv. 2020:2020.12.21.20248640. 10.1101/2020.12.21.20248640 - DOI