Thrombotic events after AstraZeneca vaccine: What if it was related to dysfunctional immune response?
- PMID: 33892936
- PMCID: PMC8057862
- DOI: 10.1016/j.therap.2021.04.003
Thrombotic events after AstraZeneca vaccine: What if it was related to dysfunctional immune response?
Erratum in
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Corrigendum to "Thrombotic events after AstraZeneca vaccine: What if it was related to dysfunctional immune response?" Therapie 2021;76:367-9.Therapie. 2025 Nov-Dec;80(6):696-697. doi: 10.1016/j.therap.2025.09.005. Epub 2025 Oct 22. Therapie. 2025. PMID: 41130876 No abstract available.
Keywords: COVID-19; Neutrophil activation; Physiopathology; Thrombosis; Vaccines.
Comment on
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Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition.Blood. 2020 Oct 29;136(18):2080-2089. doi: 10.1182/blood.2020008248. Blood. 2020. PMID: 32877502 Free PMC article.
References
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- Mahase E. Covid-19: AstraZeneca vaccine is not linked to increased risk of blood clots, finds European Medicine Agency. BMJ. 2021;372:n774. - PubMed
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- Agence nationale de sécurité du médicament et des produits de santé . 2021. Point de situation sur la surveillance des vaccins contre la COVID-19 - Enquête de pharmacovigilance du vaccin Covid-19 Vaccine AstraZeneca. Rapport n°4. https://ansm.sante.fr/actualites/point-de-situation-sur-la-surveillance-... [Accessed April 8, 2021]
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- De Santis O., Audran R., Pothin E., Warpelin-Decrausaz L., Vallotton L., Wuerzner G., et al. Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study. Lancet Infect Dis. 2016;16:311–320. doi: 10.1016/S1473-3099(15)00486-7. - DOI - PubMed
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