The burden of the Risk Evaluation and Mitigation Strategy (REMS) on providers and patients experiencing early pregnancy loss: A commentary

doi:10.1016/j.contraception.2021.04.009

. 2021 Jul;104(1):29-30.

doi: 10.1016/j.contraception.2021.04.009. Epub 2021 Apr 22.

The burden of the Risk Evaluation and Mitigation Strategy (REMS) on providers and patients experiencing early pregnancy loss: A commentary

Anne N Flynn¹, Jade M Shorter², Andrea H Roe³, Sarita Sonalkar³, Courtney A Schreiber³

Affiliations

¹ Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. Electronic address: anne.flynn@pennmedicine.upenn.edu.
² Department of Obstetrics and Gynecology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305 United States.
³ Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

PMID: 33895123
PMCID: PMC8255269
DOI: 10.1016/j.contraception.2021.04.009

The burden of the Risk Evaluation and Mitigation Strategy (REMS) on providers and patients experiencing early pregnancy loss: A commentary

Anne N Flynn et al. Contraception. 2021 Jul.

. 2021 Jul;104(1):29-30.

doi: 10.1016/j.contraception.2021.04.009. Epub 2021 Apr 22.

Authors

Anne N Flynn¹, Jade M Shorter², Andrea H Roe³, Sarita Sonalkar³, Courtney A Schreiber³

Affiliations

¹ Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. Electronic address: anne.flynn@pennmedicine.upenn.edu.
² Department of Obstetrics and Gynecology, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305 United States.
³ Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

PMID: 33895123
PMCID: PMC8255269
DOI: 10.1016/j.contraception.2021.04.009

No abstract available

Keywords: Early pregnancy loss; Mifepristone; Risk Evaluation and Mitigation Strategy (REMS).

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: Dr. Schreiber has received consulting fees from Danco laboratories. No other potential conflict of interest relevant to this article was reported.

Cited by

Management of early pregnancy loss by reproductive endocrinologists: does access to mifepristone matter?
Anderson ZS, Paulson RJ, Nguyen BT. Anderson ZS, et al. F S Rep. 2024 May 22;5(3):252-258. doi: 10.1016/j.xfre.2024.05.005. eCollection 2024 Sep. F S Rep. 2024. PMID: 39381661 Free PMC article.
Outcomes After Early Pregnancy Loss Management With Mifepristone Plus Misoprostol vs Misoprostol Alone.
Benson LS, Gunaje N, Holt SK, Gore JL, Dalton VK. Benson LS, et al. JAMA Netw Open. 2024 Oct 1;7(10):e2435906. doi: 10.1001/jamanetworkopen.2024.35906. JAMA Netw Open. 2024. PMID: 39378038 Free PMC article.
Mifepristone for miscarriage treatment in Utah: A survey of clinician knowledge and assessment of an educational video on future use.
Kaiser JE, Kurtz T, Glasser A, Brintz BJ, Gawron LM, Turok DK, Sanders JN. Kaiser JE, et al. AEM Educ Train. 2022 Dec 20;6(6):e10834. doi: 10.1002/aet2.10834. eCollection 2022 Dec. AEM Educ Train. 2022. PMID: 36562027 Free PMC article.
Medical management of early pregnancy loss is cost-effective compared with office uterine aspiration.
Nagendra D, Gutman SM, Koelper NC, Loza-Avalos SE, Sonalkar S, Schreiber CA, Harvie HS. Nagendra D, et al. Am J Obstet Gynecol. 2022 Nov;227(5):737.e1-737.e11. doi: 10.1016/j.ajog.2022.06.054. Epub 2022 Jun 30. Am J Obstet Gynecol. 2022. PMID: 35780811 Free PMC article. Clinical Trial.

References

1. Warburton D and Fraser FC, Spontaneous Abortion Risksin Man: Data from Reproductive Histories Collected in a Medical Genetics Unit. Am J Hum Genet, 1964. 16: p. 1–25. - PMC - PubMed
1. Ventura SJ, et al., Estimated pregnancy rates and rates of pregnancy outcomes for the United States, 1990–2008. Natl Vital Stat Rep, 2012. 60(7): p. 1–21. - PubMed
1. Zhang J, et al., A comparison of medical management with misoprostol and surgical management for early pregnancy failure. N Engl J Med, 2005. 353(8): p. 761–9. - PubMed
1. Robledo C, et al., Clinical indicators for success of misoprostol treatment after early pregnancy failure. Int J Gynaecol Obstet, 2007. 99(1): p. 46–51. - PMC - PubMed
1. Schreiber CA, et al., Mifepristone and misoprostol for the treatment of early pregnancy failure: a pilot clinical trial. Contraception, 2006. 74(6): p. 458–62. - PubMed

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Grants and funding

R01 HD071920/HD/NICHD NIH HHS/United States

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations
Medical
- MedlinePlus Health Information

[1] Warburton D and Fraser FC, Spontaneous Abortion Risksin Man: Data from Reproductive Histories Collected in a Medical Genetics Unit. Am J Hum Genet, 1964. 16: p. 1–25. - PMC - PubMed

[2] Warburton D and Fraser FC, Spontaneous Abortion Risksin Man: Data from Reproductive Histories Collected in a Medical Genetics Unit. Am J Hum Genet, 1964. 16: p. 1–25. - PMC - PubMed

[3] Ventura SJ, et al., Estimated pregnancy rates and rates of pregnancy outcomes for the United States, 1990–2008. Natl Vital Stat Rep, 2012. 60(7): p. 1–21. - PubMed

[4] Ventura SJ, et al., Estimated pregnancy rates and rates of pregnancy outcomes for the United States, 1990–2008. Natl Vital Stat Rep, 2012. 60(7): p. 1–21. - PubMed

[5] Zhang J, et al., A comparison of medical management with misoprostol and surgical management for early pregnancy failure. N Engl J Med, 2005. 353(8): p. 761–9. - PubMed

[6] Zhang J, et al., A comparison of medical management with misoprostol and surgical management for early pregnancy failure. N Engl J Med, 2005. 353(8): p. 761–9. - PubMed

[7] Robledo C, et al., Clinical indicators for success of misoprostol treatment after early pregnancy failure. Int J Gynaecol Obstet, 2007. 99(1): p. 46–51. - PMC - PubMed

[8] Robledo C, et al., Clinical indicators for success of misoprostol treatment after early pregnancy failure. Int J Gynaecol Obstet, 2007. 99(1): p. 46–51. - PMC - PubMed

[9] Schreiber CA, et al., Mifepristone and misoprostol for the treatment of early pregnancy failure: a pilot clinical trial. Contraception, 2006. 74(6): p. 458–62. - PubMed

[10] Schreiber CA, et al., Mifepristone and misoprostol for the treatment of early pregnancy failure: a pilot clinical trial. Contraception, 2006. 74(6): p. 458–62. - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

The burden of the Risk Evaluation and Mitigation Strategy (REMS) on providers and patients experiencing early pregnancy loss: A commentary

Affiliations

The burden of the Risk Evaluation and Mitigation Strategy (REMS) on providers and patients experiencing early pregnancy loss: A commentary

Authors

Affiliations

Conflict of interest statement

Similar articles

Cited by

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical